University of Guelph

About: University of Guelph is a education organization based out in Guelph, Ontario, Canada. It is known for research contribution in the topics: Population & Gene. The organization has 26542 authors who have published 50553 publications receiving 1715255 citations. The organization is also known as: U of G & Guelph University.

Gendering organizational analysis

Abstract: Introduction PART ONE: ORGANIZATIONAL ANALYSIS: A CRITIQUE Differential Recruitment and Control - Joan Acker and Donald R Van Houten The Sex Structuring of Organizations Room For Women - Peta Tancred-Sheriff and E Jane Campbell A Case Study in the Sociology of Organizations Gender and Organizations - Jeff Hearn and P Wendy Parkin A Selective Review and a Critique of a Neglected Area PART TWO: TOWARDS FEMINISM AS RADICAL ORGANIZATIONAL ANALYSIS Sex and Organizational Analysis - Gibson Burrell Organization, Gender and Culture - Albert J Mills A Feminist Perspective on State Bureaucracy - Judith Grant and Peta Tancred-Sheriff PART THREE: FROM THEORY TO APPLICATION: EXPLORATIONS IN FEMINIST ORGANIZATIONAL ANALYSIS Sex Ratios, Sex Role Spillover and Sex at Work - Barbara A Gutek and Aaron Groff Cohen A Comparison of Men's and Women's Experiences Women Managers' Perceptions of Gender and Organizational Life - Deborah Sheppard 'The Clerking Sisterhood' - Susan Porter Benson Rationalization and the Work Culture of Saleswomen in American Department Stores 1890-1960 Merit and Gender - Clare Burton Organizations and the Mobilization of Masculine Bias PART FOUR: CONTEMPORARY VOICES An/Other Silent Voice? - Marta B Calas Representing 'Hispanic Women' in Organizational Texts Using the 'F' Word - Marta B Calas and Linda Smircich Feminist Theories and the Social Consequences of Organizational Research Re-Visioning Women Managers' Lives - Ella Louise Bell and Stella Nkomo Gendering Organizational Theory - Joan Acker

Microcolony formation: a novel biofilm model of Pseudomonas aeruginosa for the cystic fibrosis lung

Abstract: Pseudomonas aeruginosa colonizing the lung of cystic fibrosis patients is responsible for a decline in health and poor prognosis for these patients. Once established, growth of P. aeruginosa in microcolonies makes it very difficult to eradicate the organisms by antimicrobial treatment. An artificial sputum medium was developed to mimic growth of P. aeruginosa in the cystic fibrosis lung habitat and it was found that the organisms grew in tight microcolonies attached to sputum components. Several genes, such as algD, oprF and lasR but not fliC, were required for tight microcolony formation. Among the sputum components, amino acids, lecithin, DNA, salt and low iron were required for tight microcolony formation. Amino acids were also shown to be responsible for various other cystic-fibrosis-specific phenotypes of P. aeruginosa, such as diversification of colony morphology, alterations in LPS structure and hyperexpression of OprF. Since the amino acid content of sputum is elevated in severe lung disease, it is suggested that the tight microcolony biofilm is maintained in these conditions and that they contribute to the vicious cycle of disease severity and failure to eradicate the organism. Thus, growth of P. aeruginosa in artificial sputum medium is an appropriate model of chronic lung colonization and may be useful for evaluating therapeutic procedures and studying antibiotic-resistance mechanisms.

Are all n-3 polyunsaturated fatty acids created equal?

Abstract: N-3 Polyunsaturated fatty acids have been shown to have potential beneficial effects for chronic diseases including cancer, insulin resistance and cardiovascular disease. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in particular have been studied extensively, whereas substantive evidence for a biological role for the precursor, alpha-linolenic acid (ALA), is lacking. It is not enough to assume that ALA exerts effects through conversion to EPA and DHA, as the process is highly inefficient in humans. Thus, clarification of ALA's involvement in health and disease is essential, as it is the principle n-3 polyunsaturated fatty acid consumed in the North American diet and intakes of EPA and DHA are typically very low. There is evidence suggesting that ALA, EPA and DHA have specific and potentially independent effects on chronic disease. Therefore, this review will assess our current understanding of the differential effects of ALA, EPA and DHA on cancer, insulin resistance, and cardiovascular disease. Potential mechanisms of action will also be reviewed. Overall, a better understanding of the individual role for ALA, EPA and DHA is needed in order to make appropriate dietary recommendations regarding n-3 polyunsaturated fatty acid consumption.

Two Types of GGE Biplots for Analyzing Multi-Environment Trial Data

Abstract: SA genotype main effect plus genotype x environment interaction (GGE) biplot graphically displays the genotypic main effect (G) and the genotype x environment interaction (GE) of the multienvironment trial (MET) data and facilitates visual evaluation of both the genotypes and the environments. This paper compares the merits of two types of GGE biplots in MET data analysis. The first type is constructed by the least squares solution of the sites regression model (SREG 2 ), with the first two principal components as the primary and secondary effects, respectively. The second type is constructed by Mandel's solution for sites regression as the primary effect and the first prindpal component extracted from the regression residual as the secondary effect (SREG M+1 ). Results indicate that both the SREG 2 biplot and the SREG M+1 biplot are equally effective in displaying the which-won-where pattern of the MET data, although the SREG 2 biplot explains slightly more GGE variation. The SREG M+1 biplot is more desirable, however, in that it always explicitly indicates the average yield and stability of the genotypes and the discriminating ability and representativeness of the test environments.