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Institution

University of Guelph

EducationGuelph, Ontario, Canada
About: University of Guelph is a education organization based out in Guelph, Ontario, Canada. It is known for research contribution in the topics: Population & Gene. The organization has 26542 authors who have published 50553 publications receiving 1715255 citations. The organization is also known as: U of G & Guelph University.


Papers
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Journal ArticleDOI
TL;DR: The importance of lipid raft signalling in the pathogenesis of a variety of conditions, such as Alzheimer's, Parkinson's, cardiovascular and prion diseases, systemic lupus erythematosus and HIV, has been elucidated over recent years and makes these specific membrane domains an interesting target for pharmacological approaches in the cure and prevention of these diseases.

287 citations

Journal ArticleDOI
17 Dec 2015-Nature
TL;DR: It is shown that hydromagnetic turbulence in rapidly rotating protoneutron stars produces an inverse cascade of energy, and a large-scale, ordered toroidal field is found that is consistent with the formation of bipolar magnetorotationally driven outflows.
Abstract: Magnetohydrodynamic turbulence is important in many high-energy astrophysical systems, where instabilities can amplify the local magnetic field over very short timescales. Specifically, the magnetorotational instability and dynamo action have been suggested as a mechanism for the growth of magnetar-strength magnetic fields (of 10^(15) gauss and above) and for powering the explosion of a rotating massive star. Such stars are candidate progenitors of type Ic-bl hypernovae, which make up all supernovae that are connected to long γ-ray bursts. The magnetorotational instability has been studied with local high-resolution shearing-box simulations in three dimensions, and with global two-dimensional simulations, but it is not known whether turbulence driven by this instability can result in the creation of a large-scale, ordered and dynamically relevant field. Here we report results from global, three-dimensional, general-relativistic magnetohydrodynamic turbulence simulations. We show that hydromagnetic turbulence in rapidly rotating protoneutron stars produces an inverse cascade of energy. We find a large-scale, ordered toroidal field that is consistent with the formation of bipolar magnetorotationally driven outflows. Our results demonstrate that rapidly rotating massive stars are plausible progenitors for both type Ic-bl supernovae and long γ-ray bursts, and provide a viable mechanism for the formation of magnetars. Moreover, our findings suggest that rapidly rotating massive stars might lie behind potentially magnetar-powered superluminous supernovae.

287 citations

Journal ArticleDOI
TL;DR: In this article, the authors extended the notions of essential smoothness, essential strict convexity, and Legendreness for convex functions from Euclidean to Banach spaces and proved that every Legendre function on a reflexive Banach space is zone consistent.
Abstract: The classical notions of essential smoothness, essential strict convexity, and Legendreness for convex functions are extended from Euclidean to Banach spaces. A pertinent duality theory is developed and several useful characterizations are given. The proofs rely on new results on the more subtle behavior of subdifferentials and directional derivatives at boundary points of the domain. In weak Asplund spaces, a new formula allows the recovery of the subdifferential from nearby gradients. Finally, it is shown that every Legendre function on a reflexive Banach space is zone consistent, a fundamental property in the analysis of optimization algorithms based on Bregman distances. Numerous illustrating examples are provided.

287 citations

Journal ArticleDOI
TL;DR: The F WMFs in the Beaufort-Chukchi Seas region were consistent with reported values in the Canadian Arctic and temperate food webs, but were statistically different than FWMFs from the Barents and White Seas, indicating that the spatial variability of OC contamination in top-level marine Arctic predators is attributed to differences in regional sources of contamination rather than trophic position.

286 citations

Journal ArticleDOI
TL;DR: Given their important role in bacterial cell wall metabolism, the lytic transglycosylases may present an attractive new target for the development of broad-spectrum antibiotics.

286 citations


Authors

Showing all 26778 results

NameH-indexPapersCitations
Dirk Inzé14964774468
Norbert Perrimon13861073505
Bobby Samir Acharya1331121100545
Eduardo Marbán12957949586
Benoît Roux12049362215
Fereidoon Shahidi11995157796
Stephen Safe11678460588
Mark A. Tarnopolsky11564442501
Robert C. Haddon11257752712
Milton H. Saier11170754496
Hans J. Vogel111126062846
Paul D. N. Hebert11153766288
Peter T. Katzmarzyk11061856484
John Campbell107115056067
Linda F. Nazar10631852092
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202368
2022391
20212,575
20202,547
20192,264
20182,155