University of Guelph

About: University of Guelph is a education organization based out in Guelph, Ontario, Canada. It is known for research contribution in the topics: Population & Gene. The organization has 26542 authors who have published 50553 publications receiving 1715255 citations. The organization is also known as: U of G & Guelph University.

Discovering the best web service

Abstract: Major research challenges in discovering Web services include, provisioning of services across multiple or heterogeneous registries, differentiating between services that share similar functionalities, improving end-to-end Quality of Service (QoS), and enabling clients to customize the discovery process. Proliferation and interoperability of this multitude of Web services have lead to the emergence of new standards on how services can be published, discovered, or used (i.e. UDDI, WSDL, SOAP). Such standards can potentially provide many of these features and much more, however, there are technical challenges associated with existing standards. One of these challenges is the client.s ability to control the discovery process across accessible service registries for finding services of interest. This work proposes a solution to this problem and introduces the Web Service Relevancy Function (WsRF) used for measuring the relevancy ranking of a particular Web service based on QoS metrics and client preferences. We present experimental validation, results, and analysis of the presented ideas.

Turn-of-month and pre-holiday effects on stock returns: Some international evidence

Abstract: This study examines turn-of-month and pre-holiday effects on international markets. Turn-of-month effects are significant in Canada, the UK, Australia, Switzerland, and West Germany. Pre-holiday effects are significant in Canada, Japan, Hong Kong, and Australia. The absence of these effects in certain markets suggests that they originate from country-specific institutional practices. All countries exhibiting pre-holiday effects do so before local holidays; only Hong Kong does so before US holidays. This reinforces the conclusion that such anomalies are not generated solely by American institutions.

The Behavioral Ecology of Intermittent Locomotion1

Abstract: Most physiological and ecological approaches to animal locomotion are based on steady state assumptions, yet movements of many animals are interspersed with pauses lasting from milliseconds to minutes. Thus, pauses, along with changes in the duration and speed of moves, form part of a dynamic system of intermittent locomotion by which animals adjust their locomotor behavior to changing circumstances. Intermittent locomotion occurs in a wide array of organisms from protozoans to mammals. It is found in aerial, aquatic and terrestrial locomotion and in many behavioral contexts including search and pursuit of prey, mate search, escape from predators, habitat assessment and general travel. In our survey, animals exhibiting intermittent locomotion paused on average nearly 50% of their locomotion time (range 6–94%). Although intermittent locomotion is usually expected to increase energetic costs as a result of additional expenditure for acceleration and deceleration, a variety of energetic benefits can arise when forward movement continues during pauses. Endurance also can be improved by partial recovery from fatigue during pauses. Perceptual benefits can arise because pauses increase the capacity of the sensory systems to detect relevant stimuli. Several processes, including velocity blur, relative motion detection, foveation, attention and interference between sensory systems are probably involved. In animals that do not pause, alternative mechanisms for stabilizing the perceptual field are often present. Because movement is an important cue for stimulus detection, pauses can also reduce unwanted detection by an organism's predators or prey. Several models have attempted to integrate energetic and perceptual processes, but many challenges remain. Future advances will require improved quantification of the effects of speed on perception.

Engraftment of Bone Marrow from Severe Combined Immunodeficient (SCID) Mice Reverses the Reproductive Deficits in Natural Killer Cell–deficient tgε26 Mice

Abstract: A large, transient population of natural killer (NK) cells appears in the murine uterine mesometrial triangle during pregnancy. Depletion of uterine (u) NK cells, recently achieved using gene-ablated and transgenic mice, results in pathology. Pregnancies from matings of homozygous NK and T cell-deficient tg epsilon 26 mice have <1% of normal uNK cell frequency, no development of an implantation site-associated metrial gland, and an edematous decidua with vascular pathology that includes abnormally high vessel walls/lumens ratios. Fetal loss of 64% occurs midgestation and placentae are small. None of these features are seen in pregnant T cell-deficient mice. To confirm the role of the NK cell deficiency in these reproductive deficits, transplantation of tg epsilon 26 females was undertaken using bone marrow from B and T cell-deficient scid/scid donors. Engrafted pregnant females have restoration of the uNK cell population, induced metrial gland differentiation, reduced anomalies in the decidua and decidual blood vessels, increased placental sizes, and restoration of fetal viability at all gestational days studied (days 10, 12, and 14). Thus, uNK cells appear to have critical functions in pregnancy that promote decidual health, the appropriate vascularization of implantation sites, and placental size.