Uzhhorod National University

About: Uzhhorod National University is a education organization based out in Uzhhorod, Ukraine. It is known for research contribution in the topics: Raman spectroscopy & Laser. The organization has 1089 authors who have published 1056 publications receiving 5187 citations. The organization is also known as: State Higher Education Establishment "Uzhhorod National University" & Uzhhorod State University.

Outlook for the treatment and prognosis of high-grade brain gliomas

Abstract: Malignant gliomas account up to 38% of primary brain tumors and tend to grow up for the last 30 years. The median survival time for patients with glioblastomas after surgery, followed by a combination of radiation and chemotherapy is 14.6 months. The standard for surgical treatment of malignant gliomas is their maximal safe resection. Increase resection provides patients’ survival increasing, but there are no randomized controlled trials on this subject. For the last years significant progress was marked in understanding of pathogenesis mechanisms of malignant gliomas that opens new possibilities for their treatment improvement. The purpose of the report was to analyze the modern advances in treatment of patients with high-grade brain gliomas and to identify promising directions for future researches. Modern features of surgical treatment as well as additional methods (radiation and chemotherapy) were considered, promising researches were identified.

Numerical-analytic method for the investigation of boundary-value problems for semilinear systems of differential equations

Abstract: We propose a new numerical-analytic algorithm for the investigation of boundary-value problems for semilinear systems of differential equations.

Quantum chemical insight on the uranyl benzoates association with cetylpyridinium

Abstract: The possibility of analytical determination of the uranyl cation UO22+ (taken in the form of the complex uranyl benzoate anion) by using the potentiometric titration technique has been theoretically investigated via DFT modeling and OPLS-AA force field molecular dynamics. The results of the quantum chemical calculations indicate that, among the benchmarked candidate carboxylate anions, the benzoate anion is seemingly characterized by the optimum combination of the binding properties for complexation with the uranyl cation: it shows a relatively high binding to the uranyl cation and, simultaneously, a high binding of the formed uranyl benzoate anion to the cetylpyridinium cation used as a titrant. Moreover, among the considered uranyl-carboxylate anions, the uranyl benzoate anion has been found to be the most lipophilic, which characterizes this form as the most suitable for uranyl determination.

On the Moment-Generating Functions of Extrema and Their Complements for Almost Semicontinuous Integer-Valued Poisson Processes on Markov Chains

Abstract: For an integer-valued compound Poisson process with geometrically distributed jumps of a certain sign [these processes are called almost upper (lower) semicontinuous] defined on a finite regular Markov chain, we establish relations (without projections) for the moment-generating functions of extrema and their complements. Unlike the relations obtained earlier in terms of projections, the proposed new relations for the moment-generating functions are determined by the inversion of the perturbed matrix cumulant function. These matrix relations are expressed via the moment-generating functions for the distributions of the corresponding jumps.