Uzhhorod National University

About: Uzhhorod National University is a education organization based out in Uzhhorod, Ukraine. It is known for research contribution in the topics: Raman spectroscopy & Laser. The organization has 1089 authors who have published 1056 publications receiving 5187 citations. The organization is also known as: State Higher Education Establishment "Uzhhorod National University" & Uzhhorod State University.

Optical characteristics and parameters of gas-discharge plasma on mixtures of mercury dichloride vapor and neon

Abstract: The results of studies of the optical characteristics and parameters of DBD (dielectric barrier discharge) plasma on a mixture of mercury dichloride vapor, neon are presented. The following functions were established: EEDF, transport characteristics, specific discharge power losses on electronic processes, electrons’ concentration and temperature, rate constants for elastic and inelastic electron scattering on components of the working mixture, depending on the E/N.

Priorities of anti-hyperglycaemic drug therapy in patients with type 2 diabetes and heart failure.

Abstract: Objective The aim is to explore the possibilities of improving the effectiveness in preventing cardiovascular diseases and heart failure using sodium-glucose co-transporter 2 inhibitors. Patients and methods Materials and methods: The analysis of the existing clinical and experimental data on the effect of sodium-glucose co-transporter 2 (SGLT-2) inhibitors on the cardiovascular system, the condition of kidneys, cardiovascular risk factors. Results Review: SGLT-2 inhibitors are the first class of glucose-lowering agents in large-scale studies (EMPA-REG OUTCOME, CANVAS, CVD-REAL, CVD-REAL2) which have demonstrated the ability to improve cardiorenal outcomes and reduce the risk of hospitalization with heart failure in patients with diabetes. In addition to hypoglycaemic action, SGLT-2 inhibitors show a number of pleiotropic effects, which are potentially capable of reducing cardiovascular risk: diuretic effect, decrease in: blood pressure, arterial wall stiffness, waist and body weight, expression of albuminuria, etc. The use of drugs of this class opens great prospects not only in terms of glycaemic control, but also in the prevention of cardiovascular complications of diabetes. Conclusion Conclusions: 1. When choosing glucose-lowering agents in patients with type 2 diabetes, it is necessary to take into account their impact on the risk of development and the course of heart failure. 2. SGLT-2 inhibitors ought to be considered as a preferred method of treatment for type 2 diabetes in patients with heart failure or with a risk of heart failure that meets the latest recommendations of the European and American Diabetes Association.

Conceptual problems of investigation and prevention of enforced disappearance of persons in the conditions of armed aggression

Abstract: The article highlights the results of a study of the situation with official investigations into criminal offenses related to the enforced disappearance of persons in the context of armed aggression in eastern and southern Ukraine. The example of individual criminal proceedings presents some systemic problems that arise during the investigation of the facts of disappearance and suggests possible ways to solve them. There are several «blocks» of problems that lie in the field of criminal law, criminology, and criminal procedure. The points of view of scientists and practitioners on this problem are highlighted. It is concluded that Ukraine, in today’s conditions, needs to take measures aimed at improving the legal mechanisms of observance and protection of the right of persons staying in its territory to freedom from enforced disappearance, as well as intensifying law enforcement agencies to prompt, complete and impartial investigation of such facts, their proper qualification, search for victims, identification of those responsible for their disappearance, ensuring that victims receive timely and adequate compensation. The methodological basis for writing the article was a dialectical-materialist method, as well as the set of general scientific and special methods and techniques of scientific knowledge.

Spectrophotometric Determination of the Total Iodine Content in Drinking and Mineral Waters Using the Microextraction Preconcentration

Abstract: Optimal conditions for the microextraction concentration and spectrophotometric determination of iodine (I, V, VII) forms as ionic associates of triiodide anions with the cation of astrazone brilliant red 4G dye have been found. A new procedure for the spectrophotometric determination of the total iodine content in drinking and mineral waters with the detection limit of 8.9 μg/dm3 was developed and tested. This procedure is combined with microextraction concentration and meets the requirements of “green” chemistry.