Uzhhorod National University

About: Uzhhorod National University is a education organization based out in Uzhhorod, Ukraine. It is known for research contribution in the topics: Raman spectroscopy & Laser. The organization has 1089 authors who have published 1056 publications receiving 5187 citations. The organization is also known as: State Higher Education Establishment "Uzhhorod National University" & Uzhhorod State University.

Direct observation of the photoinduced evolution of the plastic properties of glassy semiconductors

Abstract: The evolution of the plastic properties of chalcogenide glassy semiconductor films continuously irradiated by light in the spectral region of intrinsic absorption has been studied. The photoinduced variation of plasticity (photoplastic effect) exhibits a two-stage character, whereby an intermediate metastable phase is formed in the first stage. The plasticity of this phase is higher than that of the light-stable phase formed upon prolonged irradiation. In both stages, the photoplastic effect was quantitatively characterized by viscosity measured using a microindentation technique. The most pronounced photoplastic effect is observed in freshly deposited As50Se50 films, the viscosity of which changes from ∼1.5×1012 P in the initial stage (giant photosoftening) to ∼6×1014 P in the final stage.

Morphometric and electron microscopic changes of structural components of lymph nodes during correction of the action of sodium glutamate with orlistat.

Abstract: OBJECTIVE The aim: To study morphometric and electron microscopic changes in the parenchyma of rat lymph nodes under the action of sodium glutamate and its correction by orlistat. PATIENTS AND METHODS Materials and methods: The article presents and analyzes the data of an experimental study conducted on 66 white male rats and females of reproductive age. Experimental animals are divided into 4 groups. RESULTS Results: After six weeks of exposure to monosodium glutamate, there was a significant decrease in the relative area of the cortical substance in the lymph nodes of white male and female rats by 11.95% and 9.31% and, respectively, an increase in the relative area of the medullary substance by 18.76% and 14.7% in compared with an intact group of animals. After six weeks of sodium glutamate and the next six weeks of the standard diet of vivarium and orlistat, the relative area of the cortical substance in the lymph node parenchyma was 2.55% and 0.38% more than the parameters of the intact group of animals, respectively. Accordingly, the relative area of the medullary substance decreased and was 4.01% and 0.59% less compared to the intact group of animals. CONCLUSION Conclusions: Electron microscopic examination showed that monosodium glutamate causes changes in the parenchyma of the lymph nodes as in a high-calorie diet. The introduction of orlistat (xenical) leads to a partial restoration of the structural organization, and hence the function of this organ.

Species Composition and Quantitative Development of Benthic Rotifera in the Uzh River (the Basin of the Tisa River) within the Territory of Ukraine

Abstract: A. A. KovalchukUzhgorod National UniversityUzhgorod, UkraineThe species composition of benthic Rotifera of the Uzh River (the basin ofthe Tisa River) and seasonal dynamics of their quantitative characteristics wereinvestigated. The influence of the peculiarities of the section of the river andseason on dynamics of Rotifera numbers and biomass was assessed.

Venous hemodynamics in acute varicothrombophlebitis in the great saphenous vein basin

Abstract: Objective. To evaluate the influence of venous hemodynamics in acute varicothrombophlebitis in the basin of the great saphenous vein on the spread of the thrombotic process. Materials and methods. The analysis of venous hemodynamic disorders in 245 patients with acute varicothrombophlebitis in the basin of the great saphenous vein was performed. The age of patients participating in the study ranged from 19 to 82 years (mean age 52±2,7 years). There were 93 men (38.0%) and 152 women (62.0%). The laboratory and instrumental methods were used for all the patients. They included doppler ultrasound and ultrasound duplex scanning. («ULTIMA PRO–30, zone Ultra», ZONARE Medical Systems Inc., USA). Results. When AVTF occurred in the GSV basin, all patients showed reflux in the superficial veins of the lower extremities. The ultrasound scanning was performed at the initial examination and immediately before urgent surgery for AVTF. The data of color duplex mapping allowed to reveal certain regularities of venous blood flow disturbance in AVTF and divided patients depending on the state of venous blood flow in the GSV basin into 5 groups. Each of these groups of patients, depending on the prevalence of venous reflux in the GSV pool, was divided into two subgroups: local and widespread reflux. It should be noted, that the conditions for the detection of total reflux in ATVF, with the involvement of GSV in the pathological process, were not due to thrombotic lesions of the latter. When venous reflux was detected, the elasticity and extensibility of the vein wall at the apex of thrombotic masses were evaluated. The ratio of the diameters of the GSV in these positions and the assessment of the "degree of elasticity" by Schwalb PG (2005), which indirectly characterized the state of venous tone were calculated. Venous reflux was assessed on a Valsalva test in vertical and horizontal positions. Venous reflux of blood in the femoral veins was found in 134 (54.7%) patients. At the same time, local reflux was found in 38 (15.5%), and widespread in 96 (39.2%) patients. It should be noted that the prevalence of venous reflux was directly proportional to its power. Among all groups of patients with acute varicothrombophlebitis, 176 (71.8%) had widespread reflux in the great saphenous vein and 96 (39.2%) in the femoral vein. In 37 (15.1%) patients with acute varicothrombophlebitis revealed a combined nature of reflux, ie the spread of reflux from the superficial venous system not only to the apex of thrombotic masses, but also to the site of horizontal perforation, and reflux from the deep venous system spread through failed perineal veins in the great saphenous vein. Thus, widespread venous reflux was found in 87.3% of patients. In the absence of vertical reflux through the sapheno-femoral cochlea and the presence of an ascending process of thrombosis, it is necessary to identify another source of reflux. Conclusions. It is proved that the process of thrombosis in acute varicothrombophlebitis depends on the power of venous reflux, the severity of venous discharge through the communicating veins, the state of collateral venous blood flow in venous shunts and basins of large and small subcutaneous venous blood vessels. Venous reflux in the trunk of the great saphenous vein to some extent determines the embolism of the thrombus and participates in its development. Varicose veins of the great saphenous vein and the discharge of blood through incapable permeable veins reduce the power of reflux through the sapheno-femoral cochlea and reduce the rate of thrombosis in the main trunk.

State characteristics of the problem of oral cavity environmental system.

Abstract: OBJECTIVE The aim: Analysis of literary sources with the study of modern views on the problem of the immune status of the oral mucosa. PATIENTS AND METHODS Materials and methods: The review and analysis of scientific and medical literature for the years 2013-2019, based on Scopus databases, Web of Science, Med Line, The Cochrane Library, EMBASE, Global Health, CyberLeninka, RIC. CONCLUSION Conclusions: Bacterial wall antigens are able to affect the local immune response of the oral mucosa. In particular, suppression of lymphocytes and macrophages proliferation, alteration of adhesion molecules expression and homing of the immune system cells to the inflammation site, inhibition of cytokine secretion by contact of the immune system cells with gram-positive bacteria is revealed. Therefore, studying the changes in the differentiation of the oral mucosa epithelium and periodontal tissues under the influence of environmental factors is of relevance. The conception of the oral cavity as a complex ecological system has not only theoretical but also practical value. Summarizing the data, we can say that at the current stage of science development the interaction of all structures should be considered, focusing on epitheliocytes of the oral mucosa, as a closing chain, which initiates changes that can affect the condition of the oral cavity and the results of pathological processes treatment of the oral cavity mucous membrane and periodontal tissues.