Uzhhorod National University

About: Uzhhorod National University is a education organization based out in Uzhhorod, Ukraine. It is known for research contribution in the topics: Raman spectroscopy & Laser. The organization has 1089 authors who have published 1056 publications receiving 5187 citations. The organization is also known as: State Higher Education Establishment "Uzhhorod National University" & Uzhhorod State University.

Complex visual assessment of structural changes in pancreas in the patients with chronic pancreatitis.

Abstract: Chronic pancreatitis is one of the leading gastroenterologic disorders which is characterised by polymorphism of clinical manifestations, polyetiologic course and, usually, polymorbidity. The presence of such a combination of signs makes both diagnosis and treatment more difficult. This is why nowadays it is necessary to use a range of clinical, laboratory and instrumental methods of a diagnostic endeavour in order to make a diagnosis and determine the state of the pancreas. The aim of this study - to investigate and analyse structural changes in the pancreas in chronic pancreatitis in the anamnestic and clinical dimensions. In the present study, in order to achieve our aim 102 patients with chronic pancreatitis underwent general physical and laboratory examination. All the patients experienced hypertension II as a comorbid condition. In the formed group, female patients prevailed (55,9%) with the average age being 51,0±10,0 years. The duration of chronic pancreatitis was within a range of 7,0±3,0 years, whereas the hypertension duration range was 5,0±2,0 years. The following instrumental examination procedures were performed: sonographic examination of the abdominal cavity, esophagogastroduodenoscopy, duodenal drainage and endoscopic retrograde cholangiopancreatography (ERCP). Apart from hypertension, the patients with chronic pancreatitis belonging to the treatment group were diagnosed with other morphological and functional disorders related to the endocrine system, the digestive system and cardiovascular system which were revealed with the use of additional laboratory and instrumental methods. When the clinical picture was assessed on admission to hospital, all the patients presented with pain dyspeptic syndrome and exocrine pancreatic insufficiency in different proportions. 12 patients with chronic pancreatitis, whose clinical picture showed a marked pain abdominal syndrome, the intensity of which did not subside during 3 weeks of background therapy, and the absence of dynamic changes according to the ultrasound examination of the pancreas, underwent the additional diagnostic procedure ERCP to identify structural changes of the pancreatic ducts and parenchymatous parameters of the pancreas. The findings were as follows: the signs of the dilation of the major pancreatic duct were identified in all examined patients (100%), which did not coincide with the data provided by the ultrasound examination; the dilation of the small pancreatic ducts was found in 2 (16,7%) patients, lithiasis of Wirsung's duct in 3 (25,0%) patients; the combination of cystic transformation and calcinosis of the major pancreatic duct in 1 patient (8,4%); and cystic transformation in combination with the dilation of the duct of Wirsung in 2 (16,7%) patients. The imaging of structural changes in the pancreas requires the combination of instrumental and diagnostic methods, in particular EGD and ultrasound examination, as well as ERCP in order to make accurate assessment of the pancreatic ducts and parenchymatous parameters of the pancreas in case of a relapsing course of disease. The analysis of the identified disorders of the pancreatic ducts and parenchyma makes it possible to adjust treatment protocols to provide proper clinical care to patients with chronic pancreatitis.

Phase Equilibria in the TlInSe 2 –TlInP 2 Se 6 –Tl 4 P 2 Se 6 Quasiternary System

Abstract: Creation of new materials with a complex of predicted properties is the most important task of the modern inorganic science.

Regioselectivity of Intramolecular Electrophilic Cyclization of 2-(Alkenylsulfanyl)thieno[2,3-d]pyrimidin-4(3H)-ones with p-Methoxyphenyltellurium Trichloride

Abstract: 3-Phenyl-2-(prop-2-en-1-ylsulfanyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one reacted with 4-methoxyphenyltellurium trichloride in a regioselective manner to give angularly fused 1-{[dichloro(4-methoxyphenyl)-λ4-tellanyl]methyl}-4-oxo-5-phenyl-1,2,4,5,6,7,8,9-octahydrobenzo[4,5]thieno[3,2-e][1,3]thiazolo[3,2-a]pyrimidinium chloride. Electrophilic cyclization of 2-(prop-2-en-1-ylsulfanyl)- and 2-(2-methylprop-2-en-1-ylsulfanyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-ones with 4-methoxyphenyltellurium trichloride afforded linearly fused 3-{[dichloro(4-methoxyphenyl)-λ4-tellanyl]methyl}-2,3,6,7,8,9-hexahydro-5H-benzo[4,5]thieno[2,3-d][1,3]thiazolo[3,2-a]pyrimidin-5-one hydrochlorides. Regardless of the reactant ratio, the products were isolated as 1:1 complexes with 4-methoxyphenyltellurium trichloride.

Electron temperature and concentration in the laser erosion plasma of lead and gallium

Abstract: Time-averaged values of the electron temperature and concentration at distances of 1 and 7 mm from a target have been determined from the emission characteristics of the laser erosion plasma of lead and gallium. The plasma was produced in a vacuum (3–12 Pa) as the corresponding target was exposed to radiation of a neodymium laser (τ = 20 ns, λ = 1.06 μm, f = 12 Hz, W = 108–109 W/cm2). The energy distribution of excited atomic states has been analyzed. The time dependence of the electron temperature at a distance of 7 mm from the target is presented.

Electronic and optical properties of gyrotropic α-Hg 3 S 2 Cl 2 : insights from an ab initio study

Abstract: The optical spectra of gyrotropic α-Hg3S2Cl2 polymorph were calculated for the first time to give a deep insight into its band structure. The exchange–correlation potential was treated with the generalized gradient approximation and modified Becke–Johnson potential (MBJ) to improve the accuracy of electronic structure calculation. The detailed analysis of the low-energy electronic states near the Fermi level was conducted. The main contributions of the sulfur and chlorine p states are located at the top of the valence band, while the S/p and Hg/s states give main contribution to the bottom of the conduction band. The direct optical band gap of 3.19 eV is at the Г-points of Brillouin zone. The value of direct optical transitions, which was calculated by MBJ method, agrees very well with the experimental report on diffuse reflectance spectra. The reported structural and optical properties of α-Hg3S2Cl2 polymorph make it a potentially interesting compound for nonlinear optical applications.