Uzhhorod National University

About: Uzhhorod National University is a education organization based out in Uzhhorod, Ukraine. It is known for research contribution in the topics: Raman spectroscopy & Laser. The organization has 1089 authors who have published 1056 publications receiving 5187 citations. The organization is also known as: State Higher Education Establishment "Uzhhorod National University" & Uzhhorod State University.

Heat capacity and electrical resistance of (PbySn1-y)2P2S6 chalcogenides

Abstract: We present the results of study of heat capacity and electrical resistance of the (PbySn1-y)2P2S6 chalcogenides where Pb content varies from 0 till 0.8. We have studied the temperature behaviour of heat capacity from the point of Pb influence on change of transition temperature at the temperature region 50–400 K Moreover, we present the results of study of temperature dependence of electrical resistance and influence of an applied magnetic field up to 3 T The electrical resistance was studied in the temperature range 50–400 K due to low temperature semiconducting behaviour. We studied the influence of Pb content on phase transition and relaxation processes.

Optical diagnostics of lead and PbGa2S4 layered crystal laser plasmas

Abstract: Laser plasmas produced at the surfaces of lead and a PbGa2S4 layered crystal irradiated by a neodymium laser with λ=1.06 µm, pulse duration τ=20 ns, and intensity W=(1–2)×109 W/cm2 are studied using optical diagnostics. It is shown that, in a lead plasma, the most intense (characteristic) lines are the PbI 405.7-nm, PbI 368.3-nm, PbI 364-nm, and PbII 220.4-nm lines. In a layered crystal plasma, the emission spectrum is an aggregation of the most intense PbI and GaI lines, whereas sulfur lines are absent. The bottlenecks of the recombination of the ionic and atomic components of the lead and PbGa2S4 crystal plasmas are determined. The average propagation velocity of the lead laser plume is 18–20 km/s. A comparative analysis of the emission dynamics of PbI and GaI lines in the laser plasmas of these metals and in the plasma of a PbGa2S4 crystal is carried out. The results obtained are important for the optical diagnostics of the plasmas of leadand gallium-containing crystals and for the optimization of laser deposition of the thin films of these substances.

Peculiarities of changes in homocysteine levels depending on vitamin status in patients with chronic pancreatitis and type 2 diabetes.

Abstract: OBJECTIVE The aim: To determine the peculiarities of changes in the homocysteine levels in the patients with chronic pancreatitis and type 2 diabetes blood serum depending on the vitamin status. PATIENTS AND METHODS Materials and methods: We investigated 36 patients with chronic pancreatitis and type 2 diabetes, who were included in the first group of the patients examined; Group 2 consisted of 34 patients with chronic pancreatitis; and Group 3 of the patients examined consisted of 40 patients with type 2 diabetes. RESULTS Results: All patients examined were diagnosed with type 2 diabetes mellitus of moderate severity. Also, the diagnosis of chronic pancreatitis was confirmed in all patients with type 2 diabetes, which was manifested by exocrine pancreatic insufficiency according to the results of clinical, laboratory and instrumental methods of examination. There was a significant decrease in the level of all B vitamins and 25-(OH)D in patients with chronic pancreatitis and type 2 diabetes (Group I). An increase in the concentration of homocysteine in the serum in all examined groups of patients was established, with the maximum deviation from the norm in patients with chronic pancreatitis and type 2 diabetes (up to 32.7 ± 0.8 μmol / L <0.01). The correlation analysis revealed a strong direct relationship between the level of homocysteine and vitamins B12, B6, 25-(OH)D and an inverse correlation between vitamin B9 in the group of patients with chronic pancreatitis and type 2 diabetes. CONCLUSION Conclusions: Patients with chronic pancreatitis and type 2 diabetes have a decreased levels of B vitamins (B1, B6, B9, B12) and 25-(OH)D, which is accompanied by an increase in serum homocysteine. In patients with chronic pancreatitis and type 2 diabetes, the level of homocysteine in the blood serum directly depends on the decrease in the levels of vitamins B6, B12 and 25-(OH)D in blood serum, as well as inverse depends on vitamin B9 levels in these patients.

Use of polymethine dyes for the extraction separation and spectrophotometric determination of nitrophenols

Abstract: The extraction of nitrophenols with polymethine dyes of the common formula R1-(CH=CH)3-R2, indolium and benzothiazolium derivatives was studied. The effect of the acidity of the solution, the nature and the concentration of the dye, and the nature of the organic solvent on the formation and extraction of ion pairs of nitrophenols was examined; the optimum conditions were found. The most important chemical analytical characteristics of the ion pairs were determined. Molar absorptivities of extracts are 11.9 × 104–14.3 × 104 for ion pairs of trinitrophenol and 6.8 × 104–10.1 × 104 for ion pairs of dinitrophenol. A new procedure was developed for the extraction-photometric determination of nitrophenols in a mixture.

Loop diuretics in heart failure: evidence-based choice.

Abstract: Objective The aim: Of the article is to conduct a comparative evaluation of the effectiveness of torasemide and furosemide in patients with heart failure. Patients and methods Materials and methods: Analysis of the existing clinical trials and meta-analyzes that combine the results of the completed studies aimed at the investigation of comparative efficacy of furosemide and torasemide in patients with heart failure (НF). Conclusion Conclusions: There is enough convincing evidence to speak about the advantages of torasemide over furosemide both in terms of its pharmacological properties and taking into account the reduction of hospitalizations, functional progress and improvement in the quality of life of patients with НF. The safety profile of torasemide is more favorable, as it is associated with a reduced risk of hypokalemia compared to furosemide. The abovementioned facts favor the use of torasemide in patients with symptomatic НF, as well as the transition from furosemide to torasemide in patients with edema caused by НF, which remain uncontrolled despite receiving optimal doses of furosemide.