Institution
Wayne State University
Education•Detroit, Michigan, United States•
About: Wayne State University is a education organization based out in Detroit, Michigan, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 42801 authors who have published 82738 publications receiving 3083713 citations. The organization is also known as: WSU & Wayne University.
Topics: Population, Cancer, Poison control, Pregnancy, Medicine
Papers published on a yearly basis
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TL;DR: The effect of interactions among tumor cells, stromal cells, and the extracellular matrix on the regulation of protease expression is discussed and the role of inhibitors and novel protease-based drugs for clinical use are discussed.
598 citations
Rutgers University1, University of California, San Francisco2, University of Texas MD Anderson Cancer Center3, Washington University in St. Louis4, University of Chicago5, Emory University6, Princess Margaret Cancer Centre7, University of Calgary8, University of South Florida9, Mayo Clinic10, Cleveland Clinic11, City of Hope National Medical Center12, Wayne State University13, University of British Columbia14, University of Pennsylvania15, Onyx Pharmaceuticals16, Icahn School of Medicine at Mount Sinai17
TL;DR: Durable responses and an acceptable tolerability profile in this heavily pretreated population demonstrate the potential of carfilzomib to offer meaningful clinical benefit.
598 citations
TL;DR: There is a renewed interest in the antimicrobial properties of spices in the last decade as mentioned in this paper, and several ground spices, their water and alcohol extracts, and their essential oils have been demonstrated in culture media.
Abstract: There is a renewed interest in the antimicrobial properties of spices. In vitro activities of several ground spices, their water and alcohol extracts, and their essential oils have been demonstrated in culture media. Studies in the last decade confirm growth inhibition of gram positive and gram negative food borne bacteria, yeast and mold by garlic, onion, cinnamon, cloves, thyme, sage and other spices. Effects in foods are limited to observations in pickles, bread, rice, and meat products. In general, higher spice levels are required to effect inhibition in foods than in culture media. Fat, protein, and water contents in foods affect microbial resistance as does salt content. Very few studies report on the effect of spices on spores, and on microbial inhibition in conjunction with preservatives and food processes. Of the recognized antimicrobial components in spices, the majority are phenol compounds with a molecular weight of 150 to 160 containing a hydroxyl group. Eugenol, carvacrol and thymol have been identified as the major antimicrobial compounds in cloves, cinnamon, sage and oregano.
596 citations
University of Pennsylvania1, Ain Shams University2, Mayo Clinic3, University at Buffalo4, Case Western Reserve University5, Harvard University6, Duke University7, National Institutes of Health8, McGill University9, Indiana University10, Wayne State University11, Louisiana State University12, University of Texas Southwestern Medical Center13, Icahn School of Medicine at Mount Sinai14
TL;DR: In this review, the evidence underlying a wide variety of IGIV uses is evaluated and specific recommendations on the basis of these data are made.
Abstract: Human immunoglobulin prepared for intravenous administration (IGIV) has a number of important uses in the treatment of disease. Some of these are in diseases for which acceptable treatment alternatives do not exist. In this review we have evaluated the evidence underlying a wide variety of IGIV uses and make specific recommendations on the basis of these data. Given the potential risks and inherent scarcity of IGIV, careful consideration of the indications for and administration of IGIV is warranted.
595 citations
TL;DR: In this article, the authors presented a method for the optimisation of the lowest energy point of the intersection of two potential energy surfaces, which avoids the use of Lagrange multipliers.
595 citations
Authors
Showing all 43073 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Robert Langer | 281 | 2324 | 326306 |
| Eugene Braunwald | 230 | 1711 | 264576 |
| Rakesh K. Jain | 200 | 1467 | 177727 |
| Anil K. Jain | 183 | 1016 | 192151 |
| Richard A. Gibbs | 172 | 889 | 249708 |
| Bradley Cox | 169 | 2150 | 156200 |
| Jun Wang | 166 | 1093 | 141621 |
| David Altshuler | 162 | 345 | 201782 |
| Elliott M. Antman | 161 | 716 | 179462 |
| Jovan Milosevic | 152 | 1433 | 106802 |
| Roberto Romero | 151 | 1516 | 108321 |
| Kypros H. Nicolaides | 147 | 1302 | 87091 |
| John F. Hartwig | 145 | 714 | 66472 |
| Charles Maguire | 142 | 1197 | 95026 |
| Mingshui Chen | 141 | 1543 | 125369 |