A dimensional approach to the psychosis spectrum between bipolar disorder and schizophrenia: the Schizo-Bipolar Scale.
Matcheri S. Keshavan,David W. Morris,John A. Sweeney,Godfrey D. Pearlson,Gunvant K. Thaker,Larry J. Seidman,Shaun M. Eack,Carol A. Tamminga +7 more
TLDR
The data suggest a hybrid conceptualization model with a representation of cases with prototypic schizophrenia or bipolar disorder at the extremes, but a large group of patients on the continuum between them that traditionally would be considered schizoaffective.About:
This article is published in Schizophrenia Research.The article was published on 2011-12-01 and is currently open access. It has received 176 citations till now. The article focuses on the topics: Bipolar disorder & Schizoaffective disorder.read more
Citations
More filters
Journal ArticleDOI
The Chronnectome: Time-Varying Connectivity Networks as the Next Frontier in fMRI Data Discovery
TL;DR: This Perspective uses the term "chronnectome" to describe metrics that allow a dynamic view of coupling and focuses on multivariate approaches developed in the group and review a number of approaches with an emphasis on matrix decompositions such as principle component analysis and independent component analysis.
Journal ArticleDOI
Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers
Brett A. Clementz,John A. Sweeney,Jordan P. Hamm,Elena I. Ivleva,Lauren E. Ethridge,Godfrey D. Pearlson,Matcheri S. Keshavan,Carol A. Tamminga +7 more
TL;DR: These data illustrate how multiple pathways may lead to clinically similar psychosis manifestations, and they provide explanations for the marked heterogeneity observed across laboratories on the same biomarker variables when DSM diagnoses are used as the gold standard.
Journal ArticleDOI
Characterizing Thalamo-Cortical Disturbances in Schizophrenia and Bipolar Illness
Alan Anticevic,Michael W. Cole,Grega Repovs,John D. Murray,Margaret S. Brumbaugh,Anderson M. Winkler,Aleksandar Savić,John H. Krystal,John H. Krystal,Godfrey D. Pearlson,David C. Glahn +10 more
TL;DR: Classification and cross-diagnostic results suggest that thalamic dysconnectivity may be a neural marker for disturbances across diagnoses, and basic understanding of large-scale thalamo-cortical systems is informed.
Journal ArticleDOI
Dynamic connectivity states estimated from resting fMRI Identify differences among Schizophrenia, bipolar disorder, and healthy control subjects
Barnaly Rashid,Barnaly Rashid,Eswar Damaraju,Eswar Damaraju,Godfrey D. Pearlson,Vince D. Calhoun +5 more
TL;DR: The results provide new information about these illnesses and strongly suggest that state-based analyses are critical to avoid averaging together important factors that can help distinguish these clinical groups.
Journal ArticleDOI
Neuropsychological Impairments in Schizophrenia and Psychotic Bipolar Disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Study
S. Kristian Hill,James L. Reilly,Richard S.E. Keefe,James M. Gold,Jeffrey R. Bishop,Elliot S. Gershon,Carol A. Tamminga,Godfrey D. Pearlson,Matcheri S. Keshavan,John A. Sweeney +9 more
TL;DR: Robust cognitive deficits are present and familial in schizophrenia and psychotic bipolar disorder and Severity of cognitive impairments across psychotic disorders was consistent with a continuum model, in which more prominent affective features and less enduring psychosis were associated with less cognitive impairment.
References
More filters
Journal ArticleDOI
Intraclass correlations: uses in assessing rater reliability.
TL;DR: In this article, the authors present guidelines for choosing among six different forms of the intraclass correlation for reliability studies in which n target are rated by k judges, and the confidence intervals for each of the forms are reviewed.
Journal ArticleDOI
The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia
TL;DR: Review of five studies involving the PANSS provided evidence of its criterion-related validity with antecedent, genealogical, and concurrent measures, its predictive validity, its drug sensitivity, and its utility for both typological and dimensional assessment.
Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
TL;DR: The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.
Journal ArticleDOI
Research diagnostic criteria: Rationale and reliability.
TL;DR: The development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC), indicate high reliability for diagnostic judgments made using these criteria.
Related Papers (5)
The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
Shaun Purcell,Shaun Purcell,Naomi R. Wray,Jennifer Stone,Jennifer Stone,Peter M. Visscher,Michael Conlon O'Donovan,Patrick F. Sullivan,Pamela Sklar,Pamela Sklar,Douglas M. Ruderfer,Andrew McQuillin,Derek W. Morris,Colm O'Dushlaine,Aiden Corvin,Peter Holmans,Stuart MacGregor,Hugh Gurling,Douglas Blackwood,Nicholas John Craddock,Michael Gill,Christina M. Hultman,Christina M. Hultman,George Kirov,Paul Lichtenstein,Walter J. Muir,Michael John Owen,Carlos N. Pato,Edward M. Scolnick,Edward M. Scolnick,David St Clair,Nigel Williams,Lyudmila Georgieva,Ivan Nikolov,Nadine Norton,Hywel Williams,Draga Toncheva,Vihra Milanova,Emma Flordal Thelander,Patrick Sullivan,Elaine Kenny,Emma M. Quinn,Khalid Choudhury,Susmita Datta,Jonathan Pimm,Srinivasa Thirumalai,Vinay Puri,Robert Krasucki,Jacob Lawrence,Digby Quested,Nicholas Bass,Caroline Crombie,Gillian Fraser,Soh Leh Kuan,Nicholas Walker,Kevin A. McGhee,Ben S. Pickard,P. Malloy,Alan W Maclean,Margaret Van Beck,Michele T. Pato,Helena Medeiros,Frank A. Middleton,Célia Barreto Carvalho,Christopher P. Morley,Ayman H. Fanous,David V. Conti,James A. Knowles,Carlos Ferreira,António Macedo,M. Helena Azevedo,Andrew Kirby,Andrew Kirby,Manuel A. R. Ferreira,Manuel A. R. Ferreira,Mark J. Daly,Mark J. Daly,Kimberly Chambert,Finny G Kuruvilla,Stacey Gabriel,Kristin G. Ardlie,Jennifer L. Moran +81 more
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
Jordan W. Smoller,Kenneth S. Kendler,Nicholas John Craddock,Phil Lee,Benjamin M. Neale,John I. Nurnberger,Stephan Ripke,Susan L. Santangelo,Patrick F. Sullivan,Shaun Purcell,Richard Anney,Jan K. Buitelaar,Ayman H. Fanous,Stephen V. Faraone,Witte J.G. Hoogendijk,Klaus-Peter Lesch,Douglas F. Levinson,Roy H. Perlis,Marcella Rietschel,Brien P. Riley,Edmund J.S. Sonuga-Barke,Russell Schachar,Thomas G. Schulze,Anita Thapar,Michael C. Neale,Patrick Bender,Sven Cichon,Mark J. Daly,John R. Kelsoe,Thomas Lehner,Michael Conlon O'Donovan,Pablo V. Gejman,Jonathan Sebat,Pamela Sklar +33 more