Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
Citations
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Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra,Gitishree Das,Leonardo Fernandes Fraceto,Leonardo Fernandes Fraceto,Estefania Vangelie Ramos Campos,Estefania Vangelie Ramos Campos,Maria del Pilar Rodriguez-Torres,Laura Susana Acosta-Torres,Luis A. Diaz-Torres,Renato Grillo,Mallappa Kumara Swamy,Shivesh Sharma,Solomon Habtemariam,Han-Seung Shin +13 more
TL;DR: An updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs and selective diagnosis through disease marker molecules is presented.
Journal ArticleDOI
Designing hydrogels for controlled drug delivery.
Jianyu Li,David J. Mooney +1 more
TL;DR: This Review discusses how different mechanisms interact and can be integrated to exert fine control in time and space over the drug presentation, and collects experimental release data from the literature and presents quantitative comparisons between different systems to provide guidelines for the rational design of hydrogel delivery systems.
Journal ArticleDOI
Alginate derivatization: a review of chemistry, properties and applications.
Siddhesh N. Pawar,Kevin J. Edgar +1 more
TL;DR: Progress towards controlled synthesis of alginate derivatives, and the properties and applications of these derivatives are reviewed.
Journal ArticleDOI
3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications
Kajsa Markstedt,Athanasios Mantas,Ivan Tournier,Héctor Martínez Ávila,Daniel Hägg,Paul Gatenholm +5 more
TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
Journal ArticleDOI
A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings
TL;DR: In this article, the authors present the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications.
References
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Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: a combined computational and experimental approach.
TL;DR: This study shows that in MC3T3 preosteoblasts focal adhesion kinase (FAK) Y397 phosphorylation, cell spreading, and osteogenic differentiation can be controlled by RGD nanopatterning, with the distribution of islands throughout the hydrogel being the most significant pattern parameter.
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Controlled degradation of hydrogels using multi-functional cross-linking molecules
TL;DR: It is hypothesized that utilization of multi-functional cross-linking molecules to form hydrogels could provide a wider range and tighter control over the degradation rates and mechanical stiffness of gels than bi- functional cross- linking molecules.
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Comparison of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in SCID mice
TL;DR: This study has used alginate hydrogels as localized delivery vehicles for VEGF and bFGF, and compared the ability of these factors to promote new blood vessel formation in the subcutaneous tissue of severe combined immunodeficient (SCID) mice.
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Evaluation of a novel alginate gel dressing: Cytotoxicity to fibroblasts in vitro and foreign‐body reaction in pig skin in vivo
Yoshihisa Suzuki,Yoshihiko Nishimura,Masao Tanihara,Kyoko Suzuki,Tatsuo Nakamura,Yasuhiko Shimizu,Yoshio Yamawaki,Yoshimi Kakimaru +7 more
TL;DR: A novel freeze-dried alginate gel dressing (AGA-100) low in calcium ions was evaluated for cytotoxicity to L929 cells in vitro and in full-thickness pig wounds in vivo and was found to be useful as anAlginate dressing.
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Hydrogels for combination delivery of antineoplastic agents.
TL;DR: A novel hydrogel is designed and synthesized to locally deliver antineoplastic agents, and the different types of release that can be achieved from these hydrogels using three model drugs: methotrexate, doxorubicin, and mitoxantrone are demonstrated.
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