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Open AccessJournal ArticleDOI

Alginate: properties and biomedical applications

Kuen Yong Lee, +1 more
- 01 Jan 2012 - 
- Vol. 37, Iss: 1, pp 106-126
TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
About
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Citations
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Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

TL;DR: A combinatorial approach for covalent chemical modification is used to generate a large library of variants of one of the most widely used hydrogel biomaterials, alginate, and identifies three triazole-containing analogs that substantially reduce foreign body reactions in both rodents and, for at least 6 months, in non-human primates.
Journal ArticleDOI

Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting

TL;DR: The application of the alginate hydrogels will be defined as drug delivery vehicles for chemotherapeutic agents and the recent advances in the application will be described later as a wound dressing and bioink in 3D bioprinting.
Journal ArticleDOI

Current advances and future perspectives of 3D printing natural-derived biopolymers.

TL;DR: This paper reviews the state-of-the-art in terms of 3D printing technology using natural-derived feedstocks, including lignocellulose, starch, algae, and chitosan-based biopolymers, and proposes a strategical development roadmap with identified material property requirements, key challenges, as well as possible solutions.
Journal ArticleDOI

3D bioprinting of a corneal stroma equivalent

TL;DR: 3D bioprinting is established to be a feasible method by which artificial corneal structures can be engineered and exhibited high cell viability both at day 1 post‐printing and at day 7.
Journal ArticleDOI

Mechanical behaviour of alginate-gelatin hydrogels for 3D bioprinting.

TL;DR: A blend of 7%Alg-8%Gel that yields high printability, mechanical strength and stiffness, and cell viability is proposed, and the compressive behaviour of Alg-Gel is found to reduce rapidly over time and especially when incubated at 37°C.
References
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Journal ArticleDOI

Chitin and chitosan: Properties and applications

TL;DR: Chitin is the second most important natural polymer in the world as mentioned in this paper, and the main sources of chitin are two marine crustaceans, shrimp and crabs, which are used for food, cosmetics, biomedical and pharmaceutical applications.
Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Angiogenesis in life, disease and medicine

TL;DR: Angiogenesis research will probably change the face of medicine in the next decades, with more than 500 million people worldwide predicted to benefit from pro- or anti-angiogenesis treatments.
Journal ArticleDOI

Biological interactions between polysaccharides and divalent cations: The egg‐box model

TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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