Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
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TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Bilayer wound dressing based on sodium alginate incorporated with curcumin-β-cyclodextrin inclusion complex/chitosan hydrogel.
Kitipong Kiti,Orawan Suwantong +1 more
TL;DR: The results showed that the SA and CS layers were successfully attached through electrostatic force and the CMx-loaded SA/CS bilayer hydrogels exhibited inhibition against both Gram-negative (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus).
Journal ArticleDOI
Tissue Engineering: An Alternative to Repair Cartilage
Yaima Campos,Amisel Almirall,Gastón Fuentes,Gastón Fuentes,Hans L Bloem,Eric L. Kaijzel,Luis J. Cruz +6 more
TL;DR: The state-of-the-art in tissue engineering for repair of articular cartilage is reviewed and the molecular, cellular, and histologic structure and function of endogenous cartil...
Journal ArticleDOI
Toward Cardiac Regeneration: Combination of Pluripotent Stem Cell-Based Therapies and Bioengineering Strategies.
Marta Mazzola,Elisa Di Pasquale +1 more
TL;DR: An up-to-date overview of the latest advancements in the application of pluripotent stem cells and tissue-engineering for therapeutically relevant cardiac regenerative approaches is provided, aiming to highlight outcomes, limitations and future perspectives for their clinical translation.
Journal ArticleDOI
Release of insulin from PLGA-alginate dressing stimulates regenerative healing of burn wounds in rats
Sandeep Dhall,João Pedro Silva,João Pedro Silva,Yan Liu,Michael Hrynyk,Monika Garcia,Alex Chan,Julia G. Lyubovitsky,Ronald J. Neufeld,Manuela Martins-Green +9 more
TL;DR: Application of ASD-containing insulin-loaded PLGA particles on burns every 3 days stimulates faster and more regenerative healing, suggesting insulin as a potential therapeutic agent in burn healing and, because of its long history of safe use in humans, could become one of the treatments of choice when repair and regeneration are critical for proper tissue function.
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Drug-impregnated, pressurized gas expanded liquid-processed alginate hydrogel scaffolds for accelerated burn wound healing.
Kelli-anne Johnson,Nicola Muzzin,Samaneh Toufanian,Rebecca A. Slick,Michael W. Lawlor,Bernhard Seifried,Paul Moquin,David R. Latulippe,Todd Hoare +8 more
TL;DR: In vivo burn wound healing assays demonstrate significantly accelerated healing with ibuprofen-loaded PGX-alginate/calcium scaffolds relative to both hydrogel-only and untreated controls, demonstrating the combined benefits of ib uprofen delivery to suppress inflammation as well as the capacity of the PGX/Calcium hydrogels to maintain wound hydration and facilitate continuous calcium release to the wound.
References
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