Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
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TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Carbohydrate-Based Macromolecular Biomaterials.
TL;DR: Carbohydrates are the most abundant and one of the most important biomacromolecules in Nature as discussed by the authors, which can be roughly divided into two categories: carbohydrates as matter and carbohydrates as information.
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The crucial role of mechanical heterogeneity in regulating follicle development and ovulation with engineered ovarian microtissue.
TL;DR: Microfluidic generation of biomimetic ovarian microtissue for miniaturized three-dimensional culture of early secondary preantral follicles by using alginate and collagen to fabricate the ovarian cortical and medullary tissues, respectively, reveals the crucial role of mechanical heterogeneity in the mammalian ovary in regulating follicle development and ovulation.
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Enzymatically-degradable alginate hydrogels promote cell spreading and in vivo tissue infiltration.
Aline Lueckgen,Daniela S. Garske,Agnes Ellinghaus,David J. Mooney,Georg N. Duda,Amaia Cipitria,Amaia Cipitria +6 more
TL;DR: This alginate-based material platform with cell-empowered enzymatic degradation could prove useful in diverse tissue engineering contexts, such as regeneration and drug delivery.
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Designing Scaffolds for Corneal Regeneration
TL;DR: Recent advancements in materials fabrication techniques such as bioprinting, electrospinning, and different collagen alignment techniques, allow scaffolds to be generated that more accurately mimic the structure of the corneal stroma.
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Polysaccharide matrices used in 3D in vitro cell culture systems.
TL;DR: This review describes how these naturally sourced biomaterials satisfy several key properties for current 3D cell culture needs and can also be synthetically modified or blended with additional components to tailor their cell engagement properties.
References
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Chitin and chitosan: Properties and applications
TL;DR: Chitin is the second most important natural polymer in the world as mentioned in this paper, and the main sources of chitin are two marine crustaceans, shrimp and crabs, which are used for food, cosmetics, biomedical and pharmaceutical applications.
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Angiogenesis in life, disease and medicine
TL;DR: Angiogenesis research will probably change the face of medicine in the next decades, with more than 500 million people worldwide predicted to benefit from pro- or anti-angiogenesis treatments.
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Biological interactions between polysaccharides and divalent cations: The egg‐box model
TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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