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Open AccessJournal ArticleDOI

Alginate: properties and biomedical applications

Kuen Yong Lee, +1 more
- 01 Jan 2012 - 
- Vol. 37, Iss: 1, pp 106-126
TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
About
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Citations
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Designing hydrogels for controlled drug delivery.

TL;DR: This Review discusses how different mechanisms interact and can be integrated to exert fine control in time and space over the drug presentation, and collects experimental release data from the literature and presents quantitative comparisons between different systems to provide guidelines for the rational design of hydrogel delivery systems.
Journal ArticleDOI

Alginate derivatization: a review of chemistry, properties and applications.

TL;DR: Progress towards controlled synthesis of alginate derivatives, and the properties and applications of these derivatives are reviewed.
Journal ArticleDOI

3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications

TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
Journal ArticleDOI

A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings

TL;DR: In this article, the authors present the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications.
References
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Journal ArticleDOI

A preliminary study comparing the use of allogenic chondrogenic pre-differentiated and undifferentiated mesenchymal stem cells for the repair of full thickness articular cartilage defects in rabbits

TL;DR: This study demonstrates that the use of either MSC or CMSC produced superior healing when compared to cartilage defects that were untreated, however, both cells produced comparable treatment outcomes.
Journal ArticleDOI

Culture of neural stem cells in calcium alginate beads.

TL;DR: It is demonstrated that N SC expansion within Ca‐Alg‐Bs is feasible and provides further possibilities for NSC expansion in bioreactors of the scale of clinical relevance.
Journal ArticleDOI

Tuneable semi-synthetic network alginate for absorptive encapsulation and controlled release of protein therapeutics.

TL;DR: SNAP, a new class of tuneable biomaterial, can be semi-synthesized with desired pore properties, which when applied with the absorptive encapsulation technique, can serve as a technology platform for oral delivery of biomolecules with wide range of molecular sizes.
Journal ArticleDOI

Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization.

TL;DR: Combined delivery of VEGF and MCP-1 increased functional vessel formation from transplanted EC and also led to a higher number of smooth muscle cell-invested vessels than did EC therapy alone, suggesting a potential benefit of combined delivery of M CP-1 and V EGF from EC-containing hydrogels as a strategy for therapeutic vascularization.
Journal ArticleDOI

Cellular therapies for liver replacement.

TL;DR: In vivo tissue engineering involves isolated liver cell transplantation into the liver and/or other ectopic sites and in vitro tissue engineering, using an extracorporeal hepatic support system or bioartificial liver, which may overcome problems associated with xenogeneic cells.
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