Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
Citations
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Controlled release of vascular endothelial growth factor from spray‐dried alginate microparticles in collagen–hydroxyapatite scaffolds for promoting vascularization and bone repair
Elaine Quinlan,Elaine Quinlan,Adolfo López-Noriega,Emmet M. Thompson,Emmet M. Thompson,Alan Hibbitts,Alan Hibbitts,Sally-Ann Cryan,Sally-Ann Cryan,Fergal J. O'Brien,Fergal J. O'Brien +10 more
TL;DR: A biologically functionalized scaffold, composed entirely of natural‐based materials, may offer an ideal platform to promote angiogenesis and tissue regeneration.
Journal ArticleDOI
Chitosan-alginate membranes accelerate wound healing
Guilherme Ferreira Caetano,Marco Andrey Cipriani Frade,Thiago Antônio Moretti de Andrade,Marcel Nani Leite,Cecilia Zorzi Bueno,Ângela Maria Moraes,João Tadeu Ribeiro-Paes +6 more
TL;DR: Chitosan-alginate membrane modulated the inflammatory phase, stimulated fibroplasia and collagenesis, accelerating wound healing process in rats, and showed faster reepithelialization on 7(th) day than SL group, although similar in other days.
Journal ArticleDOI
3D printed chitosan dressing crosslinked with genipin for potential healing of chronic wounds.
TL;DR: Cytotoxicity assay using human skin fibroblast cell lines demonstrated that more than 90% of cells were viable after 48 h confirming non‐toxic nature of the 3D printed CH‐GE‐PEG600 films and therefore promising dressing for chronic wound healing applications.
Journal ArticleDOI
A review on the synthesis of graft copolymers of chitosan and their potential applications.
Deepak Kumar,Deepak Kumar,Sachin Gihar,Manoj Kumar Shrivash,Pramendra Kumar,Patit Paban Kundu +5 more
TL;DR: In this paper, a review of graft copolymerization of chitosan is presented and the properties of grafted chitin copolymers are discussed, which is an excellent candidate for drug delivery, food packaging and wastewater treatment.
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Injectable multifunctional microgel encapsulating outgrowth endothelial cells and growth factors for enhanced neovascularization.
Pyung-Hwan Kim,Hyun-Gu Yim,Young Jin Choi,Byung-Jae Kang,Joohyun Kim,Sang-Mo Kwon,Byung-Soo Kim,Nathaniel S. Hwang,Je-Yoel Cho +8 more
TL;DR: An injectable multifunctional micro-sized gel system (microgel), composed of arginine-glycine-aspartic acid (RGD)-conjugated alginate, for the delivery of both cells and growth factors in vivo was developed and was shown to be superior with no toxicity.
References
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Chitin and chitosan: Properties and applications
TL;DR: Chitin is the second most important natural polymer in the world as mentioned in this paper, and the main sources of chitin are two marine crustaceans, shrimp and crabs, which are used for food, cosmetics, biomedical and pharmaceutical applications.
Journal ArticleDOI
Angiogenesis in life, disease and medicine
TL;DR: Angiogenesis research will probably change the face of medicine in the next decades, with more than 500 million people worldwide predicted to benefit from pro- or anti-angiogenesis treatments.
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Biological interactions between polysaccharides and divalent cations: The egg‐box model
TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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