Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
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TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra,Gitishree Das,Leonardo Fernandes Fraceto,Leonardo Fernandes Fraceto,Estefania Vangelie Ramos Campos,Estefania Vangelie Ramos Campos,Maria del Pilar Rodriguez-Torres,Laura Susana Acosta-Torres,Luis A. Diaz-Torres,Renato Grillo,Mallappa Kumara Swamy,Shivesh Sharma,Solomon Habtemariam,Han-Seung Shin +13 more
TL;DR: An updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs and selective diagnosis through disease marker molecules is presented.
Journal ArticleDOI
Designing hydrogels for controlled drug delivery.
Jianyu Li,David J. Mooney +1 more
TL;DR: This Review discusses how different mechanisms interact and can be integrated to exert fine control in time and space over the drug presentation, and collects experimental release data from the literature and presents quantitative comparisons between different systems to provide guidelines for the rational design of hydrogel delivery systems.
Journal ArticleDOI
Alginate derivatization: a review of chemistry, properties and applications.
Siddhesh N. Pawar,Kevin J. Edgar +1 more
TL;DR: Progress towards controlled synthesis of alginate derivatives, and the properties and applications of these derivatives are reviewed.
Journal ArticleDOI
3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications
Kajsa Markstedt,Athanasios Mantas,Ivan Tournier,Héctor Martínez Ávila,Daniel Hägg,Paul Gatenholm +5 more
TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
Journal ArticleDOI
A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings
TL;DR: In this article, the authors present the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications.
References
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Biodegradable, photocrosslinked alginate hydrogels with independently tailorable physical properties and cell adhesivity
TL;DR: The adhesion-ligand-modified hydrogels enhanced the proliferation and chondrogenic differentiated function of encapsulated chondrocytes as demonstrated by increased DNA content and production of glycosaminoglycans compared to unmodified controlHydrogels.
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Extended release of high pI proteins from alginate microspheres via a novel encapsulation technique.
L. A. Wells,Heather Sheardown +1 more
TL;DR: Alginate has potential as a matrix for controlled delivery of protein-based drugs that require site-specific long-term delivery and the interactions between the high pI proteins and the alginate gel could potentially be exploited to generate new protein delivery systems.
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Adhesion and growth of bone marrow stromal cells on modified alginate hydrogels.
TL;DR: It was found that, in contrast to rat cells, human cells did not readily attach or proliferate on unmodified alginates, but alginate gels containing both collagen type I and beta-tricalcium phosphate were found to enhance human cell adherence and proliferation.
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Shear-reversibly Crosslinked Alginate Hydrogels for Tissue Engineering
TL;DR: Using both ionic and cell-crosslinking methods to control the gelation behavior may allow the design of novel injectable systems that can be used to deliver cells and other therapeutics for minimally invasive therapy, including tissue engineering.
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Amphiphilic derivatives of sodium alginate and hyaluronate for cartilage repair: rheological properties.
TL;DR: Various amphiphilic derivatives of sodium alginate and hyaluronate were prepared by covalent fixation of long alkyl chains with various ratios on the polysaccharide backbones via ester functions by demonstrating tremendous enhancement of zero shear rate Newtonian viscosity, steep shear-thinning behavior, and formation of physically cross-linked gel-like networks.
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