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Open AccessJournal ArticleDOI

Alginate: properties and biomedical applications

Kuen Yong Lee, +1 more
- 01 Jan 2012 - 
- Vol. 37, Iss: 1, pp 106-126
TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
About
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Citations
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Designing hydrogels for controlled drug delivery.

TL;DR: This Review discusses how different mechanisms interact and can be integrated to exert fine control in time and space over the drug presentation, and collects experimental release data from the literature and presents quantitative comparisons between different systems to provide guidelines for the rational design of hydrogel delivery systems.
Journal ArticleDOI

Alginate derivatization: a review of chemistry, properties and applications.

TL;DR: Progress towards controlled synthesis of alginate derivatives, and the properties and applications of these derivatives are reviewed.
Journal ArticleDOI

3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications

TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
Journal ArticleDOI

A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings

TL;DR: In this article, the authors present the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications.
References
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Journal ArticleDOI

Effect of an enamel matrix protein derivative (Emdogain) on ex vivo dental plaque vitality.

TL;DR: Emdogain might have an antibacterial effect on the vitality of the ex vivo supragingival dental plaque flora, indicated by statistically highly significant reductions in terms of bacteria vitality when compared to water and EMD.
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New amphiphilic and pH-sensitive hydrogel for controlled release of a model poorly water-soluble drug.

TL;DR: It was demonstrated that the establishment of clusters inside beads by intramolecular interactions between PCL grafts of 530 g mol(-1) in salt media allowed to retain the drug and to slow down its release considerably.
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In vitro and in vivo evaluation of alginate/sol-gel synthesized aminopropyl-silicate/alginate membrane for bioartificial pancreas.

TL;DR: The data show that the membrane had the molecular weight cut-off point of between 70 and 150 kDa, and hardly inhibited the permeation of glucose and insulin, and was more stable than the well-known Alg/poly-L-lysine (PLL)/Alg microcapsule.
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Alginate microsphere filled with carbon nanotube as drug carrier.

TL;DR: The AL/CNT microspheres, with higher stability, less drug leakage and predominant sustaining release profile, showed the potential application as a drug delivery system to intestine and colon.
Journal ArticleDOI

Strong calcium phosphate cement‐chitosan‐mesh construct containing cell‐encapsulating hydrogel beads for bone tissue engineering

TL;DR: Strong, in situ hardening, and cell-seeded hydroxyapatite cements may have potential for bone tissue engineering in moderate stress-bearing applications and the use of chitosan and mesh progressively improved the mechanical properties.
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