Journal ArticleDOI
Antimicrobial activity of metals: mechanisms, molecular targets and applications
Reads0
Chats0
TLDR
The chemical and toxicological principles that underlie the antimicrobial activity of metals are described and the preferences of metal atoms for specific microbial targets are discussed.Abstract:
Metals have been used as antimicrobial agents since antiquity, but throughout most of history their modes of action have remained unclear. Recent studies indicate that different metals cause discrete and distinct types of injuries to microbial cells as a result of oxidative stress, protein dysfunction or membrane damage. Here, we describe the chemical and toxicological principles that underlie the antimicrobial activity of metals and discuss the preferences of metal atoms for specific microbial targets. Interdisciplinary research is advancing not only our understanding of metal toxicity but also the design of metal-based compounds for use as antimicrobial agents and alternatives to antibiotics.read more
Citations
More filters
Journal ArticleDOI
Bioaccumulation of heavy metals, lipid profiles, and antioxidant status of snails (Achatina achatina) around cement factory vicinities.
Regina Ngozi Ugbaja,M A Enilolobo,Adewale Segun James,T. F. Akinhanmi,Adio Jamiu Akamo,David O. Babayemi,Oladipo Ademuyiwa +6 more
TL;DR: There were negative correlations between the heavy metal levels and the activities of GST and AR as well as GSH levels, while positively correlating with LDH activity and MDA level.
Journal ArticleDOI
Influence of antibiotic adsorption on biocidal activities of silver nanoparticles.
TL;DR: Synergistic effect of SNPs on antibacterial activities of tetracycline and kanamycin has been observed and may be helpful in reducing their effective dosages.
Journal ArticleDOI
Accumulation and sublethal effects of triclosan and its transformation product methyl-triclosan in the earthworm Eisenia andrei exposed to environmental concentrations in an artificial soil.
Fanny Chevillot,Mélanie Guyot,Mélanie Desrosiers,Nicole Cadoret,Éloïse Veilleux,Hubert Cabana,Jean-Philippe Bellenger +6 more
TL;DR: It is concluded that exposure to low concentrations of triclosan in artificial soil can significantly affect the growth and reproductive performance of earthworms (i.e., E. andrei).
Journal ArticleDOI
Biohydrogen production by vermihumus-associated microorganisms using agro industrial wastes as substrate
Edén Oceguera-Contreras,Oscar Aguilar-Juárez,David Omar Oseguera-Galindo,José Macías-Barragán,Roberto Bolaños-Rosales,Mayra Mena-Enriquez,Armando Arias-García,Margarita Montoya-Buelna,Omar Graciano-Machuca,Antonio De León-Rodríguez +9 more
TL;DR: In this article, Eisenia foetida lixiviated earthworm as inoculum using agro industrial wastes as substrate was used to produce hydrogen from the recalcitrant raw materials such as sugarcane bagasse.
Journal ArticleDOI
Improving the metal ion release from nanoparticles embedded in a polypropylene matrix for antimicrobial applications
TL;DR: In this paper, the effect of different variables on the dispersion of copper metal nanoparticles embedded in a polypropylene matrix by melt mixing and its ion release was analyzed, and the results showed that by modifying these variables, a significant improvement in the filler dispersion, as quantified by optical microscope, can be obtained.
References
More filters
Journal ArticleDOI
Hard and soft acids and bases
TL;DR: In this paper, the rate data for the generalized nucleophilic displacement reaction were reviewed, and the authors presented a method to estimate the rate of the generalized displacement reaction in terms of the number of nucleophiles.
Journal ArticleDOI
Absolute hardness: companion parameter to absolute electronegativity
Robert G. Parr,Ralph G. Pearson +1 more
TL;DR: In this paper, a property called absolute hardness eta is defined for neutral and charged species, atomic and molecular, for both hard and soft acids and bases, by making use of the hypothesis that extra stability attends bonding of A to B when the ionization potentials of A and B in the molecule are the same.
Journal ArticleDOI
Shape-Controlled Synthesis of Gold and Silver Nanoparticles
Yugang Sun,Younan Xia +1 more
TL;DR: Monodisperse samples of silver nanocubes were synthesized in large quantities by reducing silver nitrate with ethylene glycol in the presence of poly(vinyl pyrrolidone) (PVP), characterized by a slightly truncated shape bounded by {100, {110}, and {111} facets.
Journal ArticleDOI
Free radicals, metals and antioxidants in oxidative stress-induced cancer
TL;DR: This review examines the evidence for involvement of the oxidative stress in the carcinogenesis process and the role of enzymatic and non-enzymatic antioxidants in the process of carcinogenesis as well as the antioxidant interactions with various regulatory factors.
Journal ArticleDOI
The bactericidal effect of silver nanoparticles
Jose Ruben Morones,Jose Luis Elechiguerra,A. Camacho,Katherine B. Holt,Juan B. Kouri,Jose Tapia Ramirez,Miguel Jose Yacaman +6 more
TL;DR: The results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.