Journal ArticleDOI
Antimicrobial activity of metals: mechanisms, molecular targets and applications
Reads0
Chats0
TLDR
The chemical and toxicological principles that underlie the antimicrobial activity of metals are described and the preferences of metal atoms for specific microbial targets are discussed.Abstract:
Metals have been used as antimicrobial agents since antiquity, but throughout most of history their modes of action have remained unclear. Recent studies indicate that different metals cause discrete and distinct types of injuries to microbial cells as a result of oxidative stress, protein dysfunction or membrane damage. Here, we describe the chemical and toxicological principles that underlie the antimicrobial activity of metals and discuss the preferences of metal atoms for specific microbial targets. Interdisciplinary research is advancing not only our understanding of metal toxicity but also the design of metal-based compounds for use as antimicrobial agents and alternatives to antibiotics.read more
Citations
More filters
Journal ArticleDOI
Incorporation of Silver Nanoparticles in Hydrogel Matrices for Controlling Wound Infection.
TL;DR: In this paper, the authors provide an up-to-date, 10-year comprehensive literature review on advancements in the understanding of AgNP characteristics, including the particles' preparation and mechanisms of activity, and explore various hydrogel scaffolds for delivering AgNPs.
Journal ArticleDOI
Progress on photocatalytic semiconductor hybrids for bacterial inactivation
TL;DR: In this article, the relevant mechanisms of the photoinduced process on the active sites of semiconductors were explored with an emphasis on the photoexcited electron transfer, ROS-induced toxicity, and interactions between semiconductorors and bacteria.
Journal ArticleDOI
Synergistic photodynamic/photothermal bacterial inactivation over heterogeneous quaternized chitosan/silver/cobalt phosphide nanocomposites.
Hecheng Han,Xiaoyan Xu,Haopeng Kan,Yunxiang Tang,Chang Liu,Hongling Wen,Lili Wu,Yanyan Jiang,Zhou Wang,Jiurong Liu,Feng-Lian Wang +10 more
TL;DR: In this paper , an innovative antibacterial nanoplatform based on quaternized chitosan (QCS)/ silver (Ag)/ cobalt phosphide (CoP) nanocomposites is envisaged for achieving near-infrared (NIR) laser-inducible rapid sterilisation.
Journal ArticleDOI
A comparative analyses of bioactive Cu(II) complexes using Hirshfeld surface and density functional theory (DFT) methods: DNA binding studies, cleavage and antibiofilm activities
Mohammad Usman,Farukh Arjmand,Musheer Ahmad,Mohammad Shavez Khan,Iqbal Ahmad,Sartaj Tabassum +5 more
TL;DR: In this paper, two mononuclear copper(II) complexes, [Cu(dip)2] (1) and [Cu[dimp] (2) have been synthesized and characterized thoroughly by various spectroscopic techniques and single crystal X-ray diffraction analysis.
Journal ArticleDOI
Development of transition metal oxide–kaolin composite pigments for potential application in paint systems
TL;DR: In this paper, a simplified process for synthesizing metal oxides of Cu(II, Ni(II), Cr(III), and Fe(III) imbibed kaolin pigments was presented.
References
More filters
Journal ArticleDOI
Hard and soft acids and bases
TL;DR: In this paper, the rate data for the generalized nucleophilic displacement reaction were reviewed, and the authors presented a method to estimate the rate of the generalized displacement reaction in terms of the number of nucleophiles.
Journal ArticleDOI
Absolute hardness: companion parameter to absolute electronegativity
Robert G. Parr,Ralph G. Pearson +1 more
TL;DR: In this paper, a property called absolute hardness eta is defined for neutral and charged species, atomic and molecular, for both hard and soft acids and bases, by making use of the hypothesis that extra stability attends bonding of A to B when the ionization potentials of A and B in the molecule are the same.
Journal ArticleDOI
Shape-Controlled Synthesis of Gold and Silver Nanoparticles
Yugang Sun,Younan Xia +1 more
TL;DR: Monodisperse samples of silver nanocubes were synthesized in large quantities by reducing silver nitrate with ethylene glycol in the presence of poly(vinyl pyrrolidone) (PVP), characterized by a slightly truncated shape bounded by {100, {110}, and {111} facets.
Journal ArticleDOI
Free radicals, metals and antioxidants in oxidative stress-induced cancer
TL;DR: This review examines the evidence for involvement of the oxidative stress in the carcinogenesis process and the role of enzymatic and non-enzymatic antioxidants in the process of carcinogenesis as well as the antioxidant interactions with various regulatory factors.
Journal ArticleDOI
The bactericidal effect of silver nanoparticles
Jose Ruben Morones,Jose Luis Elechiguerra,A. Camacho,Katherine B. Holt,Juan B. Kouri,Jose Tapia Ramirez,Miguel Jose Yacaman +6 more
TL;DR: The results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.