Journal ArticleDOI
Both resistance training and aerobic training reduce hepatic fat content in type 2 diabetic subjects with nonalcoholic fatty liver disease (the RAED2 Randomized Trial).
Elisabetta Bacchi,Carlo Negri,Giovanni Targher,Niccolò Faccioli,Massimo Lanza,Giacomo Zoppini,Elisabetta Zanolin,Federico Schena,Enzo Bonora,Paolo Moghetti +9 more
TLDR
This is the first randomized controlled study to demonstrate that resistance training and aerobic training are equally effective in reducing hepatic fat content among type 2 diabetic patients with NAFLD.About:
This article is published in Hepatology.The article was published on 2013-10-01. It has received 274 citations till now. The article focuses on the topics: Nonalcoholic fatty liver disease & Type 2 diabetes.read more
Citations
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Journal ArticleDOI
EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease
Giulio Marchesini,Christopher P. Day,Jean-François Dufour,Ali Canbay,Valerio Nobili,Vlad Ratziu,Herbert Tilg,Michael Roden,Amalia Gastaldelli,Hannele Yki-Järvinen,Fritz Schick,Roberto Vettor,Gema Frühbeck,Lisbeth Mathus-Vliegen +13 more
TL;DR: The final purpose is to improve patient care and awareness of the importance of NAFLD, and to assist stakeholders in the decision-making process by providing evidence-based data, which also takes into consideration the burden of clinical management for the healthcare system.
Journal ArticleDOI
Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association
Sheri R. Colberg,Ronald J. Sigal,Jane E. Yardley,Michael C. Riddell,David W. Dunstan,Paddy C. Dempsey,Edward S. Horton,Kristin Castorino,Deborah F. Tate +8 more
TL;DR: A clinically oriented review and evidence-based recommendations regarding physical activity and exercise in people with type 1 diabetes, type 2 diabetes, gestational diabetes mellitus, and prediabetes are provided.
Journal ArticleDOI
American association of clinical endocrinologists and american college of endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity.
W. Timothy Garvey,Jeffrey I. Mechanick,Elise M. Brett,Alan J. Garber,Daniel L. Hurley,Ania M. Jastreboff,Karl Nadolsky,Rachel Pessah-Pollack,Raymond A Plodkowski +8 more
TL;DR: The final recommendations recognize that obesity is a complex, adiposity-based chronic disease, where management targets both weight-related complications and adiposity to improve overall health and quality of life.
Journal ArticleDOI
Comment to: “EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease”
Jorge Fonseca,Gonçalo Nunes,Cristina Fonseca,Manuela Canhoto,Ana Teresa Barata,Carla Adriana Santos +5 more
Journal ArticleDOI
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
TL;DR: This Review highlights novel concepts related to diagnosis, risk prediction, and treatment of non-alcoholic fatty liver disease that could contribute to the development of a multidisciplinary approach for endocrinologists and hepatologists working together in the management of NAFLD.
References
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Journal ArticleDOI
Why might South Asians be so susceptible to central obesity and its atherogenic consequences? The adipose tissue overflow hypothesis
TL;DR: It is hypotheses that as obesity develops, South Asians exhaust the storage capacity of their superficial subcutaneous adipose tissue compartment before whites do and that is why they develop the metabolic complications of upper body obesity at lower absolute masses of adiposes tissue than white people.
Journal ArticleDOI
Effects of Diet and Exercise on Muscle and Liver Intracellular Lipid Contents and Insulin Sensitivity in Type 2 Diabetic Patients
Yoshifumi Tamura,Yasushi Tanaka,Fumihiko Sato,Jong Bock Choi,Hirotaka Watada,Masataka Niwa,Junichiro Kinoshita,Aiko Ooka,Naoki Kumashiro,Yasuhiro Igarashi,Shinsuke Kyogoku,Tadayuki Maehara,Masahiko Kawasumi,Takahisa Hirose,Ryuzo Kawamori +14 more
TL;DR: It was found that 2 wk of diet and exercise decreased IMCL and increased muscle insulin-mediated glucose uptake, whereas diet with or without exercise decreased IHL, these effects were evident despite a small decrease in body fat and were observed independently of fasting FFA levels.
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Effect of a 12-Month Intensive Lifestyle Intervention on Hepatic Steatosis in Adults With Type 2 Diabetes
Mariana Lazo,Steven F. Solga,Alena Horská,Susanne Bonekamp,Anna Mae Diehl,Frederick L. Brancati,Lynne E. Wagenknecht,F. Xavier Pi-Sunyer,Steven E. Kahn,Jeanne M. Clark +9 more
TL;DR: A 12-month intensive lifestyle intervention in patients with type 2 diabetes reduces steatosis and incident nonalcoholic fatty liver disease (NAFLD).
Journal ArticleDOI
Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.
Shira Zelber-Sagi,Dorit Nitzan-Kaluski,Dorit Nitzan-Kaluski,Rebecca Goldsmith,Muriel Webb,Izabel Zvibel,Ilana Goldiner,Laurie Blendis,Zamir Halpern,Zamir Halpern,Ran Oren,Ran Oren +11 more
TL;DR: Hitual leisure‐time PA, especially anaerobic, may play a protective role in NAFLD, and this association appears to be mediated by a reduced rate of abdominal obesity.
Journal ArticleDOI
Fatty Liver Disease: MR Imaging Techniques for the Detection and Quantification of Liver Steatosis
Fiona Cassidy,Fiona Cassidy,Takeshi Yokoo,Lejla Aganovic,Lejla Aganovic,Robert F. Hanna,Mark Bydder,Michael S. Middleton,Gavin Hamilton,Alyssa D. Chavez,Jeffrey B. Schwimmer,Claude B. Sirlin +11 more
TL;DR: Several magnetic resonance (MR) imaging-based techniques--including chemical shift imaging, frequency-selective imaging, and MR spectroscopy--are currently in clinical use for the detection and quantification of fat-water admixtures, with each technique having important advantages, disadvantages, and limitations.