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Open AccessJournal ArticleDOI

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

Behnood Bikdeli, +50 more
- 16 Jun 2020 - 
- Vol. 75, Iss: 23, pp 2950-2973
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.
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This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.

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Citations
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Structural Features and PF4 Functions that Occur in Heparin-Induced Thrombocytopenia (HIT) Complicated by COVID-19

TL;DR: PF4 and its role in HIT as well as in pathologies seen in CO VID-19 patients define a potential therapeutic option of using blocking antibodies in the treatment of COVID-19.
Journal ArticleDOI

A sensitive indicator for the severity of covid-19: thiol.

TL;DR: Depleted thiol status was observed in SARS-CoV-2 infection and this outcome highlights that thiols could be an impressible biomarker for predicting of the severity of COVID-19.
Journal ArticleDOI

Mortality of COVID-19 patients with vascular thrombotic complications.

TL;DR: In this article, the authors analyzed the survival of patients hospitalized with COVID-19 and who presented some vascular thrombotic complication, including DVT, pulmonary embolism (PE), ischemic stroke, and peripheral arterial Thrombosis (PAT).
Journal ArticleDOI

Infarction of the Splenium of the Corpus Callosum in the Age of COVID-19: A Snapshot in Time.

TL;DR: Infarction of the splenium of the corpus callosum is exceedingly rare and a cluster of such cases suggests COVID-19 as an inciting agent, with the mechanisms to be elucidated.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI

A pneumonia outbreak associated with a new coronavirus of probable bat origin

TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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