COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.read more
Citations
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American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: May 2021 update on the use of intermediate-intensity anticoagulation in critically ill patients.
Adam Cuker,Eric Tseng,Robby Nieuwlaat,Pantep Angchaisuksiri,Clifton Blair,Kathryn Dane,Jennifer Davila,Maria T. DeSancho,David L. Diuguid,Daniel O. Griffin,Susan R. Kahn,Frederikus A. Klok,Alfred Ian Lee,Ignacio Neumann,Ashok Pai,Marc Philip Righini,Kristen M. Sanfilippo,Deborah M. Siegal,Mike Skara,Deirdra R. Terrell,Kamshad Touri,Elie A. Akl,Imad Bou Akl,Antonio Bognanni,Mary Boulos,Romina Brignardello-Petersen,Rana Charide,Matthew T. V. Chan,Karin Lee Dearness,Andrea Darzi,Philipp Kolb,Luis Enrique Colunga-Lozano,Razan Mansour,Gian Paolo Morgano,Rami Z. Morsi,Giovanna Muti-Schünemann,Atefeh Noori,Binu A. Philip,Thomas Piggott,Yuan Qiu,Yetiani Roldan,Finn Schünemann,Adrienne Stevens,Karla Solo,Wojtek Wiercioch,Reem A. Mustafa,Reem A. Mustafa,Holger J. Schünemann,Holger J. Schünemann +48 more
TL;DR: In 2019, the American Society of Hematology (ASH) developed guidelines to support patients, clinicians, and other health care professionals in making decisions about the use of anticoagulation for thromboprophylaxis in patients with COVID-19-related critical illness who do not have confirmed or suspected venous thromboembolism (VTE) as discussed by the authors.
Journal ArticleDOI
Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks.
Rupinder Mann,Abhilash Perisetti,Mahesh Gajendran,Zainab Gandhi,Chandraprakash Umapathy,Hemant Goyal +5 more
TL;DR: This review aims to discuss epidemiological, clinical features, diagnosis, and management of human coronaviruses with a focus on SARS CoV-1, MERS-CoV, and SARScoV-2, which lead to a global pandemic.
Journal ArticleDOI
Association between antithrombin and mortality in patients with COVID-19. A possible link with obesity.
Carmine Gazzaruso,Enrico Paolozzi,Cinzia Valenti,Mauro Brocchetta,Daniela Naldani,Claudio Grignani,Fabrizio Salvucci,Francesco Marino,Adriana Coppola,Pietro Gallotti +9 more
TL;DR: The data suggest that AT is strongly associated with mortality and may be the link between obesity and a poorer prognosis in patients with COVID-19, and other studies should confirm whether AT may become a prognostic marker and a therapeutic target in CO VID-19.
Journal ArticleDOI
Thromboprophylaxis in Patients With COVID-19
Lisa K. Moores,Tobias Tritschler,Shari B. Brosnahan,Marc Carrier,Jacob F. Collen,Kevin C. Doerschug,Aaron B. Holley,Jonathan M. Iaccarino,David Jiménez,Grégoire Le Gal,Parth Rali,Philip S. Wells +11 more
TL;DR: In this paper , the authors provide separate guidance statements for VTE prevention for hospitalized patients with acute (moderate) illness and critically ill patients in the ICU, and divided each original question and resulting recommendation into two questions: standard prophylaxis vs therapeutic (or escalated dose) prophylecto-pharm-axis and standard pro-phylax vs intermediate dose proplylaxis, and no role for intermediate dose thromboprophylaxis in either setting.
References
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TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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