COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.read more
Citations
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Trends in Venous Thromboembolism Anticoagulation in Patients Hospitalized With COVID-19.
Valerie M. Vaughn,Valerie M. Vaughn,Valerie M. Vaughn,Monica L Yost,Chelsea Abshire,Scott A. Flanders,David Paje,Paul J. Grant,Scott Kaatz,Tae Kim,Geoffrey D. Barnes +10 more
TL;DR: In this article, the effect of nonadherence and anticoagulation strategies on in-hospital and 60-day mortality was assessed using multinomial logit models with inverse probability of treatment weighting.
Journal ArticleDOI
The Effect of Melatonin on Thrombosis, Sepsis and Mortality Rate in COVID-19 Patients
TL;DR: In this paper , the effect of melatonin on thrombosis, sepsis, and mortality rate in adult patients with severe coronavirus infection (COVID-19) was investigated.
Journal ArticleDOI
SARS-CoV-2: Repurposed drugs and novel therapeutic approaches—insights into chemical structure—biological activity and toxicological screening
Cristina Dehelean,Voichita Lazureanu,Dorina Coricovac,Marius Mioc,Roxana Oancea,Iasmina Marcovici,Iulia Pinzaru,Codruta Soica,Aristidis Tsatsakis,Octavian Cretu +9 more
TL;DR: A thorough analysis of repurposed drug admitted for compassionate use from a chemical structure—biological activity perspective highlighting the ADME ( absorption, distribution, metabolism, and excretion) properties and the toxicophore groups linked to potential adverse effects is presented.
Journal ArticleDOI
Safety of intermediate dose of low molecular weight heparin in COVID-19 patients.
Massimo Mattioli,Devis Benfaremo,M. Mancini,Luciano Mucci,Paola Mainquà,Antonio Polenta,Patrizia Maria Baldini,Francesca Fulgenzi,Donatella Dennetta,Samuele Bedetta,Lorenzo Gasperoni,Alessandro Caraffa,Gabriele Frausini +12 more
TL;DR: The use of an intermediate dose of LWMH appears to be feasible and data suggest safety in COVID-19 patients, although further studies are needed.
Journal ArticleDOI
COVID-19 and ischemic stroke: Mechanisms of hypercoagulability (Review)
Shuoqi Zhang,Jinming Zhang,Chunxu Wang,Xiaojing Chen,Xinyi Zhao,Haijiao Jing,Huan Liu,Zhuxin Li,Lihua Wang,Jialan Shi +9 more
TL;DR: In this article, the authors summarized the current status of research on COVID-19, hypercoagulability and ischemic stroke, and provided therapies for different mechanisms for the more effective treatment of patients with COVID•19 with acute stroke and prevent AIS during the COVID2019 pandemic.
References
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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