COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.read more
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Ocular and Systemic Complications of COVID-19: Impact on Patients and Healthcare
TL;DR: The potential complications and treatments of COVID-19 include conjunctivitis, cranial nerve palsies, and microvascular changes in the retina; most symptoms resolved over time.
Journal ArticleDOI
2019 novel coronavirus disease with secondary ischemic stroke: two case reports.
TL;DR: In this paper, two cases of coronavirus-infected pneumonia with acute ischemic stroke in middle-aged patients were reported, and they were treated with tirofiban and followed up with daily aspirin and atorvastatin.
Posted ContentDOI
High levels of plasminogen activator inhibitor-1, tissue plasminogen activator and fibrinogen in patients with severe COVID-19
David Cabrera-García,Andrea Miltiades,Samantha M. Parsons,Katerina Elisman,Mohammad Taghi Mansouri,Gebhard Wagener,Neil L. Harrison +6 more
TL;DR: In this article, the authors measured plasma levels of fibrinogen, plasminogen, tissue PLASminogen activator (t-PA) and plasmogen activation inhibitor 1 (PAI-1) in blood from 37 patients with severe coronavirus disease-19 (COVID-19) and 23 controls.
Journal ArticleDOI
Associated risk factors with disease severity and antiviral drug therapy in patients with COVID-19.
TL;DR: Age >60 years, D-dimer >0.243 µg/ml, and lower oxygenation index were associated with severe COVID-19, and in severe cases, the benefits of arbidol alone was 73.3%, which was better than ribavirin (7/17, 41.2%, P=0.029).
Journal ArticleDOI
Recomendaciones de consenso SEDAR-SEMICYUC sobre el manejo de las alteraciones de la hemostasia en los pacientes graves con infección por COVID-19
Juan V. Llau,R. Ferrandis,Pilar Sierra,Francisco Hidalgo,C. Cassinello,A. Gómez-Luque,Manuel Quintana,R. Amezaga,M. Gero,A. Serrano,P. Marcos +10 more
TL;DR: Recommendations include prophylaxis of venous thromboembolic disease in these patients, and in the peripartum, management of patients on long-term antiplatelet or anticoagulant treatment, bleeding complications in the course of the disease, and the interpretation of general alterations in haemostasis.
References
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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