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Open AccessJournal ArticleDOI

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

Behnood Bikdeli, +50 more
- 16 Jun 2020 - 
- Vol. 75, Iss: 23, pp 2950-2973
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.
About
This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.

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Citations
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Gender gap in women authors is not worse during COVID-19 pandemic: Results from Research and Practice in Thrombosis and Haemostasis

TL;DR: There was a 23% decline in first-authorship by women for COVID-19 papers compared to overall papers published in 2019, and these declines were greatest in infectious diseases, radiology, pathology, and public health.
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Preprint manuscripts and servers in the era of coronavirus disease 2019.

TL;DR: While vital in the rapid dispensation of science, preprint manuscripts promulgate their conclusions without peer review and possess the capacity to misinform.
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COVID-19: a probable role of the anticoagulant Protein S in managing COVID-19-associated coagulopathy.

TL;DR: It is speculated that the IL6-driven cytokine explosion plus hypoxemia causes a severe drop in Protein S level that exacerbates the thrombotic risk in COVID-19 patients.
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Vitamin D, infections and immunity

TL;DR: The current clinical data strongly associate vitamin D with SARS-CoV-2 infection, however a putative clinical link that at this time must still be considered hypothetical.
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Immature platelets as a biomarker for disease severity and mortality in COVID-19 patients.

TL;DR: In this article, the authors investigated whether the level of thrombopoiesis correlates with COVID-19 severity and showed that elevated initial and peak values of percentage IPF and immature platelet counts might serve as prognostic biomarkers for progression to severe conditions.
References
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Journal ArticleDOI

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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A pneumonia outbreak associated with a new coronavirus of probable bat origin

TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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