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Open AccessJournal ArticleDOI

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

Behnood Bikdeli, +50 more
- 16 Jun 2020 - 
- Vol. 75, Iss: 23, pp 2950-2973
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.
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This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.

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Citations
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COVID-19 coagulopathy and thrombosis: Analysis of hospital protocols in response to the rapidly evolving pandemic

TL;DR: This work collected and analyzed protocols from 21 US academic medical centers developed between January and May 2020 and found greatest consensus on recommendations for heparin-based pharmacologic venous thromboembolism (VTE) prophylaxis in COVID-19 patients without contraindications.
Journal ArticleDOI

Impact of COVID-19 and COVID-19 vaccination on high-risk patients with Antiphospholipid Syndrome: a nationwide survey

TL;DR: Patients with triple-positive thrombotic APS did not suffer from severe COVID-19 outcomes and CO VID-19 vaccination was well tolerated, which may reassure patients and physicians and contribute in reducing hesitancy in unvaccinated patients.
Journal ArticleDOI

Concomitant haemorrhagic syndrome and recurrent extensive arterial thrombosis in a patient with COVID-19 and acute promyelocytic leukaemia.

TL;DR: The multiple haemostasis abnormalities observed in a patient with concomitant acute promyelocytic leukaemia and COVID-19 led to the death of the patient and the clinical consequences were dramatic.
Journal ArticleDOI

Anticoagulation in COVID-19

TL;DR: For noncritically ill patients hospitalised with COVID-19, therapeutic-dose heparin appears beneficial, with a high probability of reducing the need for organ support and the progression to intubation and death, regardless of D-dimer results as discussed by the authors .
Journal ArticleDOI

Venous Thromboembolism in Hospitalized COVID-19 Patients: Systematic Review.

TL;DR: Despite the utilization of background anticoagulation, VTE incidence was historically high and future studies are needed to provide additional data to guide optimal VTE prophylaxis and diagnostic strategies.
References
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Journal ArticleDOI

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI

A pneumonia outbreak associated with a new coronavirus of probable bat origin

TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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