COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.read more
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Lipid-Modulating Agents for Prevention or Treatment of COVID-19 in Randomized Trials
Azita Hajhossein Talasaz,Azita Hajhossein Talasaz,Parham Sadeghipour,Maryam Aghakouchakzadeh,Isaac Dreyfus,Hessam Kakavand,Hamid Ariannejad,Amolika Gupta,Amolika Gupta,Mahesh V. Madhavan,Van Tassell Bw,David Jiménez,Manuel Monreal,Muthiah Vaduganathan,John Fanikos,Dave L. Dixon,Gregory Piazza,Sahil A. Parikh,Deepak L. Bhatt,Gregory Y.H. Lip,Gregory Y.H. Lip,Gregg W. Stone,Harlan M. Krumholz,Peter Libby,Samuel Z. Goldhaber,Behnood Bikdeli,Behnood Bikdeli,Behnood Bikdeli +27 more
TL;DR: In this paper, the authors summarized the ongoing or completed randomized controlled trials (RCTs) of lipid modulating agents in COVID-19 and the implications of these trials for patient management.
Journal ArticleDOI
Anticoagulation in COVID-19: a review of current literature and guidelines.
Bharat Narasimhan,Marta Lorente-Ros,Jose S Aguilar-gallardo,Christopher Perez Lizardo,Harish Narasimhan,Celia Morton,Kevin R. Donahue,Wilbert S. Aronow +7 more
TL;DR: In this paper, the burden of these thromboembolic events in coronavirus disease-2019 (COVID-19) as well as the hypothesized contributory biological mechanisms are discussed.
Riesgo trombótico y COVID-19: revisión de la evidencia actual para una mejor aproximación diagnóstica y terapéutica./ Riesgo trombótico y COVID-19: revisión de la evidencia actual para una mejor aproximación diagnóstica y terapéutica./ Thrombotic Risk and Covid-19: Review of Current Evidence for a Better Diagnostic and Therapeutic Approach.
TL;DR: The disease produced by this virus, called Covid-19, presents with variable clinical manifestations, from practically asymptomatic patients with catarrhal processes to severe pneumonias that rapidly evolve to acute respiratory distress syndrome (ARDS) and multiorgan failure.
Journal ArticleDOI
Clinical Presentation and Short- and Long-term Outcomes in Patients With Isolated Distal Deep Vein Thrombosis vs Proximal Deep Vein Thrombosis in the RIETE Registry.
Behnood Bikdeli,Cesar Caraballo,Javier Trujillo-Santos,Jean-Philippe Galanaud,B. Di Micco,Vladimir Rosa,G. Vidal Cusido,Sebastian Schellong,Meritxell Mellado,Mª del Valle Morales,O. Gavín-Sebastián,Lucia Mazzolai,Harlan M. Krumholz,Manuel Monreal +13 more
TL;DR: Results of this cohort study suggest that patients with IDDVT had a less ominous prognosis compared with patients with proximal DVT, and a potential association of thrombus location with VTE deterioration and postthrombotic syndrome.
Journal ArticleDOI
Getting to the Heart of the Matter: Myocardial Injury, Coagulopathy, and Other Potential Cardiovascular Implications of COVID-19.
TL;DR: A comprehensive literature review was performed on cardiac and vascular complications of COVID-19 infection as discussed by the authors, which revealed six possible mechanisms: direct cardiac damage, hypoxia-induced injury, inflammation, a dysfunctional endothelial response, coagulopathy, and the catecholamine stress response.
References
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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