COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TLDR
The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2020-06-16 and is currently open access. It has received 2222 citations till now. The article focuses on the topics: Platelet activation & Antithrombotic.read more
Citations
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Myocardial Injury in COVID-19 and Its Implications in Short- and Long-Term Outcomes
A Izquierdo-Marquisa,Hector Cubero-Gallego,Álvaro Aparisi,Beatriz Vaquerizo,Núria Ribas-Barquet +4 more
TL;DR: It is suggested that myocardial injury would identify COVID-19 patients with higher risk during active infection and mid-term follow-up and the optimal screening tool for residual cardiac sequelae, clinical follow- up, and the benefits of a specific cardiovascular therapy during the convalescent phase remains unknown.
Journal ArticleDOI
Influence of thromboembolic events in the prognosis of COVID-19 hospitalized patients. Results from a cross sectional study.
Francisco Purroy,Gloria Arque +1 more
TL;DR: In this article, the authors evaluated the prevalence of TEE and its relationship with in-hospital death among hospitalized patients with COVID-19 who were admitted between 1st March to 20th April 2020.
Journal ArticleDOI
Subendocardial Involvement as an Underrecognized Cardiac MRI Phenotype in Myocarditis
TL;DR: De Roos et al. as discussed by the authors explored and compared the histopathologic characteristics and clinical features and outcomes in patients with myocarditis with and without subendocardial involvement at cardiac MRI.
Journal ArticleDOI
COVID-19: Hemostatic parameters and specifics of antithrombotic treatment
I. S. Yavelov,O. M. Drapkina +1 more
TL;DR: Current approaches to prevention and treatment of thrombotic/thromboembolic complications in patients with COVID-19 are considered.
Journal ArticleDOI
Heparanase as a potential player in SARS-CoV-2 infection and induced coagulopathy.
TL;DR: In this article, the authors discuss the molecular involvement of HSPGs and heparanase in SARS-CoV-2 infection, namely cell entry and release, and the accompanied coagulopathy complications, which assumedly could be blocked by heparane inhibitors such as Heparin and Pixatimod.
References
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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