Proceedings ArticleDOI
Electrowetting-based on-chip sample processing for integrated microfluidics
Richard B. Fair,Vijay Srinivasan,Hong Ren,Philip Y. Paik,Vamsee K. Pamula,Michael G. Pollack +5 more
TLDR
In this article, results and data are reported on key aspects of sample processing protocols performed on-chip in a digital microfluidic lab on-a-chip (LABON-A-chip).Abstract:
In this work, results and data are reported on key aspects of sample processing protocols performed on-chip in a digital microfluidic lab-on-a-chip We report the results of experiments on aspects of sample processing, including on-chip preconcentration and dilution, on-chip sample injection or dispensing, and sample mixing It is shown that high speed transport and mixing of analytes and reagents can be performed using biological solutions without system contaminationread more
Citations
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Dissertation
Modeling, simulating, and controlling the fluid dynamics of electro-wetting on dielectric
TL;DR: In this paper, Walker et al. describe the modeling and simulation of a parallel-plate Electrowetting On Dielectric (EWOD) device that moves fluid droplets through surface tension effects.
Book ChapterDOI
Algorithmic Challenges in Digital Microfluidic Biochips: Protocols, Design, and Test
TL;DR: This review article will elaborate on several algorithmic challenges that arise while realizing biochemical protocols on a digital microfluidic lab-on-a-chip, and focus on certain design automation issues of sample preparation, dilution gradient generation, layout planning, and testing of DMF biochips.
Journal ArticleDOI
Re-entrant Cavities Enhance Resilience to the Cassie-to-Wenzel State Transition on Superhydrophobic Surfaces during Electrowetting.
TL;DR: The electrowetting behavior of cylindrical microposts and mushroom-shaped re-entrant microstructures, both of which afford excellent superhydrophobicity, is investigated and compared and it is demonstrated that mushroom structures indeed inhibit the Cassie-to-Wenzel transition at voltages that induce such transition on the cylindrations.
Patent
Methods for nucleic acid amplification on a printed circuit board
TL;DR: In this paper, the authors proposed a method for amplifying nucleic acid, such as DNA or RNA, on a printed circuit board (PCB) substrate using a variety of methods such as thermocycling or isothermally.
Proceedings ArticleDOI
Automated design of digital microfluidic lab-on-chip under pin-count constraints
Tao Xu,Krishnendu Chakrabarty +1 more
TL;DR: An efficient droplet manipulation method is presented for this cross-referencing technique based on a mapping of the droplet-movement problem to the clique-partitioning problem from graph theory.
References
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Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
Journal ArticleDOI
Light-driven motion of liquids on a photoresponsive surface
TL;DR: The light-driven motion of a fluid substance in a surface-modified glass tube suggests potential applicability to microscale chemical process systems.
Journal ArticleDOI
Electrochemical Principles for Active Control of Liquids on Submillimeter Scales
Benedict S. Gallardo,Vinay Gupta,Franklin D. Eagerton,Lana I. Jong,Vincent S. J. Craig,Rahul R. Shah,Nicholas L. Abbott +6 more
TL;DR: Electrochemical methods were combined with redox-active surfactants to actively control the motions and positions of aqueous and organic liquids on millimeter and smaller scales to guide droplets of organic liquids through simple fluidic networks.
Journal ArticleDOI
Dielectrophoretic liquid actuation and nanodroplet formation
TL;DR: In this article, the authors demonstrate a new class of high-speed DEP actuators, including wallless flowstructures, siphons, and nanodroplet dispensers that operate with water.
Journal ArticleDOI
Electrostatic actuation of liquid droplets for micro-reactor applications
TL;DR: In this paper, a device for the electrostatic actuation of liquid droplets on a solid surface is developed, where arrays of electrodes are micro-fabricated on a substrate, which is covered by a hydrophobic layer.