Entropic elasticity of lambda-phage DNA
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This article is published in Science.The article was published on 1994-09-09 and is currently open access. It has received 2089 citations till now.read more
Citations
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Titin PEVK segment: Charge-driven elasticity of the open and flexible polyampholyte
TL;DR: It is proposed that PEVK is not a simple entropic spring as is commonly assumed, but a highly evolved, gel-like enthalpic spring with its elasticity dominated by the sequence-specific charge interactions.
Journal ArticleDOI
Structure-Based Derivation of Protein Folding Intermediates and Energies from Optical Tweezers
TL;DR: It is demonstrated that the contour length is a useful reaction coordinate to characterize protein folding and that intrinsic extensions of protein structures should be taken into account to properly derive the conformations and energies of protein folding intermediates from single-molecule manipulation experiments.
Journal ArticleDOI
Force: a new structural control parameter?
TL;DR: Recent technical developments that allow precise force measurements on single molecules, together with numerical simulations of biomolecules under stress, offer new insight into how stress affects molecular interactions, and how large the force developed by a travelling enzyme such as RNA polymerase can be.
Journal ArticleDOI
First insights into electrografted polymers by AFM-based force spectroscopy
Stéphane Cuenot,Sabine Gabriel,Robert Jérôme,Christine Jérôme,Charles-André Fustin,A. M. Jonas,Anne-Sophie Duwez +6 more
TL;DR: In this article, the structural properties of poly-N-succinimidyl acrylate (PNSA) layers electrografted directly from a silicon substrate were investigated.
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Mechanical Response of Plectonemic DNA: An Analytical Solution
TL;DR: This work applies an elastic rod model for twisted DNA in the plectonemic regime to magnetic tweezer experiments of a DNA molecule subjected to a tensile force and a torque and extracts mechanical and geometrical quantities from the linear part of the experimental response curve.
References
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Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads
TL;DR: Deviations from the force curves predicted by the freely jointed chain model suggest that DNA has significant local curvature in solution, and the effect of bend-inducing cis-diamminedichloroplatinum (II) was large and supports the hypothesis of natural curvatures in DNA.
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Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat.
TL;DR: It is demonstrated that it is possible to determine the molar cyclization factor jM from single ligation reactions in which both circular and linear dimer DNA species are formed concurrently from linear monomers.
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Polymer conformational statistics. III. Modified Gaussian models of stiff chains
M. Fixman,J. Kovac +1 more
TL;DR: In this article, a modified Gaussian probability for intrachain distances was used to account for polymer chain stiffness or excluded volume effects in non-Newtonian viscosity theory.