Entropic elasticity of lambda-phage DNA
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This article is published in Science.The article was published on 1994-09-09 and is currently open access. It has received 2089 citations till now.read more
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Nonlinear elasticity of composite networks of stiff biopolymers with flexible linkers.
TL;DR: An effective medium theory of flexibly cross-linked stiff polymer networks by randomly oriented elastic rods connected by flexible connectors to a surrounding elastic continuum, which self-consistently represents the behavior of the rest of the network.
Journal ArticleDOI
Direct determination of DNA twist-stretch coupling
TL;DR: A very simple microscopic theory is presented predicting a value comparable to the one observed of the DNA double helix coupling between twist and stretch, which is in agreement with an independent experimental estimate recently given by Marko.
Journal ArticleDOI
Structural DNA Nanotechnology: Artificial Nanostructures for Biomedical Research
TL;DR: The basic design methods for fabricating both static and dynamic DNA nanostructures are reviewed, along with their biomedical applications in fields such as biosensing, bioimaging, and drug delivery.
Journal ArticleDOI
Non-Bias-Limited Tracking of Spherical Particles, Enabling Nanometer Resolution at Low Magnification
TL;DR: The proposed three-dimensional tracking routine for nondiffraction-limited particles is presented, which significantly reduces pixel bias and allows for increased resolution compared to that of previous methods, especially at low magnification or at high signal/noise ratio.
Journal ArticleDOI
Mechanical Fatigue in Repetitively Stretched Single Molecules of Titin
TL;DR: Because titin's molecular fatigue occurs in a physiologically relevant force range, the process may play an important role in dynamically adjusting muscle's response to the recent history of mechanical perturbations.
References
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Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads
TL;DR: Deviations from the force curves predicted by the freely jointed chain model suggest that DNA has significant local curvature in solution, and the effect of bend-inducing cis-diamminedichloroplatinum (II) was large and supports the hypothesis of natural curvatures in DNA.
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Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat.
TL;DR: It is demonstrated that it is possible to determine the molar cyclization factor jM from single ligation reactions in which both circular and linear dimer DNA species are formed concurrently from linear monomers.
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Polymer conformational statistics. III. Modified Gaussian models of stiff chains
M. Fixman,J. Kovac +1 more
TL;DR: In this article, a modified Gaussian probability for intrachain distances was used to account for polymer chain stiffness or excluded volume effects in non-Newtonian viscosity theory.