Entropic elasticity of lambda-phage DNA
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This article is published in Science.The article was published on 1994-09-09 and is currently open access. It has received 2089 citations till now.read more
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A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy
Daniela Bauer,Sarah Meinhold,Roman P. Jakob,Johannes Stigler,Johannes Stigler,Ulrich Merkel,Timm Maier,Matthias Rief,Gabriel Žoldák +8 more
TL;DR: Single-molecule force measurements are employed to scrutinize the hierarchy of intermediate structures along the folding pathway of the nucleotide binding domain (NBD) of Escherichia coli Hsp70 DnaK, a member of the sugar kinase superfamily that includes Hsp 70s and the cytoskeletal protein actin.
Journal ArticleDOI
Gemini surfactant-induced DNA condensation into a beadlike structure.
TL;DR: The results lead to a model in which, during condensation, independent beadlike structures are initially formed on DNA, and as the local density of the beads increases, they compact into higher-order structures while maintaining their independence.
Journal ArticleDOI
Helix-like biopolymers can act as dampers of force for bacteria in flows
TL;DR: It is shown that helix-like pili have the ability to act as efficient dampers of force that can, for a limited time, lower the load on the force-mediating adhesin-receptor bond on the tip of an individual pilus.
Journal ArticleDOI
Getting the feel of food structure with atomic force microscopy
TL;DR: The progress in the development of the atomic force microscope as an imaging tool and a force transducer is described, with particular reference to applications in food science.
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Perspective: Single polymer mechanics across the force regimes
TL;DR: I review theoretical and experimental results on the force-extension response of single polymers, with a focus on scaling pictures of low-force elastic regimes, and recent measurements of synthetic and biological chains that explore those regimes.
References
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Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads
TL;DR: Deviations from the force curves predicted by the freely jointed chain model suggest that DNA has significant local curvature in solution, and the effect of bend-inducing cis-diamminedichloroplatinum (II) was large and supports the hypothesis of natural curvatures in DNA.
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Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat.
TL;DR: It is demonstrated that it is possible to determine the molar cyclization factor jM from single ligation reactions in which both circular and linear dimer DNA species are formed concurrently from linear monomers.
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Polymer conformational statistics. III. Modified Gaussian models of stiff chains
M. Fixman,J. Kovac +1 more
TL;DR: In this article, a modified Gaussian probability for intrachain distances was used to account for polymer chain stiffness or excluded volume effects in non-Newtonian viscosity theory.