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Entropic elasticity of lambda-phage DNA

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This article is published in Science.The article was published on 1994-09-09 and is currently open access. It has received 2089 citations till now.

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Mechanical Properties of High-G⋅C Content DNA with A-Type Base-Stacking

TL;DR: The results show that a local, basepair configuration of DNA induced by high-G·C content influences the stretching elasticity of the polymer but that it does not affect the global, double-helix arrangement.
Journal ArticleDOI

Measuring the force of single protein molecule detachment from surfaces with AFM.

TL;DR: The mathematical expression of the Worm-Like Chain model was used to fit the stretching curves before rupture and two interpretations are suggested for the description of the AFM curves with multiple detachment events.
Journal ArticleDOI

Semiflexible polymers: dependence on ensemble and boundary orientations.

TL;DR: It is shown that the mechanical properties of a worm-like-chain (WLC) polymer, of contour length L and persistence length lambda such that t=L/lambda approximately O(1), depend both on the ensemble and the constraint on end orientations.
Journal ArticleDOI

Sacrificial bonds in polymer brushes from rat tail tendon functioning as nanoscale velcro.

TL;DR: It is proposed that sacrificial bonds significantly influence the tendon fibrils' self-organization and self-healing and therefore contribute to toughness and strength.
Journal ArticleDOI

Coarse-Grained Model DNA: Structure, Sequences, Stems, Circles, Hairpins

TL;DR: A coarse-grained model for DNA that is intended to function realistically at the level of individual bases is reported, and most qualitative properties of real DNA arise naturally from local interactions at the base-pair level.
References
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Journal ArticleDOI

Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads

TL;DR: Deviations from the force curves predicted by the freely jointed chain model suggest that DNA has significant local curvature in solution, and the effect of bend-inducing cis-diamminedichloroplatinum (II) was large and supports the hypothesis of natural curvatures in DNA.
Journal ArticleDOI

Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat.

TL;DR: It is demonstrated that it is possible to determine the molar cyclization factor jM from single ligation reactions in which both circular and linear dimer DNA species are formed concurrently from linear monomers.
Journal ArticleDOI

Polymer conformational statistics. III. Modified Gaussian models of stiff chains

M. Fixman, +1 more
TL;DR: In this article, a modified Gaussian probability for intrachain distances was used to account for polymer chain stiffness or excluded volume effects in non-Newtonian viscosity theory.
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