Entropic elasticity of lambda-phage DNA
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This article is published in Science.The article was published on 1994-09-09 and is currently open access. It has received 2089 citations till now.read more
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Journal ArticleDOI
Full Reconstruction of a Vectorial Protein Folding Pathway by Atomic Force Microscopy and Molecular Dynamics Simulations
TL;DR: A pathway for the co-translational folding of repeat proteins and have implications for mechanotransduction is suggested.
Journal ArticleDOI
Improved Approximations for Some Polymer Extension Models
TL;DR: In this paper, the authors proposed approximations for force-extension dependencies for the freely jointed chain (FJC) and worm-like chain (WLC) models as well as for extension-force dependence for the WLC model.
Book ChapterDOI
Nanoimprint Lithography – Patterning of Resists Using Molding
Helmut Schift,Anders Kristensen +1 more
TL;DR: Nanoimprint lithography (NIL) is an emerging high-resolution parallel patterning method, mainly aimed towards fields in which electron-beam and high-end photolithography are costly and do not provide sufficient resolution at reasonable throughput as mentioned in this paper.
Journal ArticleDOI
Single molecule mechanical manipulation for studying biological properties of proteins, DNA, and sugars
TL;DR: The methods and examples of SMFS by AFM are illustrated using recent advances in protein science including titin elasticity, mechanical unfolding and refolding of α-helical repeat proteins, and mechanoenzymatics of thioredoxin and titin kinase.
Journal ArticleDOI
Dynamics of DNA Polymers in Post Arrays: Comparison of Single Molecule Experiments and Simulations
TL;DR: In this article, the authors demonstrate the first direct comparison of experiments and simulations of DNA transport in a pressure-driven post array flow and demonstrate that the appropriate design of post array geometry can be used to control DNA conformation and guide the location of hooking events.
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Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads
TL;DR: Deviations from the force curves predicted by the freely jointed chain model suggest that DNA has significant local curvature in solution, and the effect of bend-inducing cis-diamminedichloroplatinum (II) was large and supports the hypothesis of natural curvatures in DNA.
Journal ArticleDOI
Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat.
TL;DR: It is demonstrated that it is possible to determine the molar cyclization factor jM from single ligation reactions in which both circular and linear dimer DNA species are formed concurrently from linear monomers.
Journal ArticleDOI
Polymer conformational statistics. III. Modified Gaussian models of stiff chains
M. Fixman,J. Kovac +1 more
TL;DR: In this article, a modified Gaussian probability for intrachain distances was used to account for polymer chain stiffness or excluded volume effects in non-Newtonian viscosity theory.