Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
Citations
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[Clinical and coagulation characteristics in 7 patients with critical COVID-2019 pneumonia and acro-ischemia].
Yan Zhang,Wei Cao,Meng Xiao,Yuanjie Li,Yang Yang,Jing Zhao,Xiang Zhou,Wei Jiang,Yongqiang Zhao,Shuyang Zhang,Taisheng Li +10 more
TL;DR: The existence of hypercoagulation status in critical COVID-2019 patients with acro-ischemia should be monitored closely, and anticoagulation therapy can be considered in selected patients.
Journal ArticleDOI
Evaluation of lockdown effect on SARS-CoV-2 dynamics through viral genome quantification in waste water, Greater Paris, France, 5 March to 23 April 2020.
Sébastien Wurtzer,Vincent Maréchal,Jean-Marie Mouchel,Yvon Maday,R Teyssou,E Richard,JL Almayrac,Laurent Moulin +7 more
TL;DR: A time-course quantitative analysis of SARS-CoV-2 genomes in WW by RT-qPCR in raw WW samples collected from several major WW treatment plants in Greater Paris showed that the increase of genome units inRaw WW accurately followed the increasing of human COVID-19 cases observed at the regional level.
Journal ArticleDOI
Organ-specific manifestations of COVID-19 infection.
Maria Gavriatopoulou,Eleni Korompoki,Eleni Korompoki,Despina Fotiou,Ioannis Ntanasis-Stathopoulos,Theodora Psaltopoulou,Efstathios Kastritis,Evangelos Terpos,Meletios A. Dimopoulos +8 more
TL;DR: A comprehensive overview of the organ-specific systemic manifestations of COVID-19 is provided, showing that over a third of infected patients develop a broad spectrum of neurological symptoms affecting the central nervous system, peripheral nervous system and skeletal muscles, including anosmia and ageusia.
Journal ArticleDOI
Effects of the COVID-19 pandemic on anxiety and depressive symptoms in pregnant women: a preliminary study.
Ferit Durankuş,Erson Aksu +1 more
TL;DR: The effects of the COVID-19 pandemic on the depression and anxiety levels of pregnant women point to an urgent need to provide psychosocial support to this population during the crisis.
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Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2.
Yanxiao Han,Petr Král +1 more
TL;DR: Molecular dynamics simulations revealed that the α-helical peptides maintain their secondary structure and provide a highly specific and stable binding (blocking) to SARS-CoV-2.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
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TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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