Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
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Clinical Characteristics of and Medical Interventions for COVID-19 in Hemodialysis Patients in Wuhan, China.
Fei Xiong,Hui Tang,Li Liu,Can Tu,Jian Bo Tian,Chun Tao Lei,Jing Liu,Jun Wu Dong,Wen Li Chen,Xiao Hui Wang,Dan Luo,Ming Shi,Xiaoping Miao,Chun Zhang +13 more
TL;DR: It is found that patients receiving maintenance hemodialysis were susceptible to COVID-19 and that he modialysis centers were high-risk settings during the epidemic, and that increasing prevention efforts, instituting universal screening, and isolating patients with COIDs and directing them to designated heModialysis center were effective in preventing the spread.
Journal ArticleDOI
Overview of lethal human coronaviruses.
Bin Chen,Er Kang Tian,Bin He,Lejin Tian,Ruiying Han,Wang Shuangwen,Qianrong Xiang,Shu Zhang,Toufic El Arnaout,Wei Cheng +9 more
TL;DR: Recent studies are summarized and reviewed, with a focus on virus–host interactions, vaccine-based and drug-targeted therapies, and the development of new approaches for clinical diagnosis and treatment of coronavirus infections of multiple origins.
Posted ContentDOI
Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial.
Peter Horby,M Mafham,Louise Linsell,Jennifer L Bell,Natalie Staplin,Jonathan Emberson,Martin Wiselka,Andrew Ustianowski,E Elmahi,B Prudon,A Whitehouse,Timothy Felton,John Williams,J Faccenda,Jonathan Underwood,J K Baillie,Lucy C Chappell,Saul N. Faust,Thomas Jaki,Katie Jeffery,Wei Shen Lim,Alan A Montgomery,Kathy Rowan,Joel Tarning,James A Watson,Nicholas J. White,Edmund Juszczak,Richard Haynes,Martin J Landray +28 more
TL;DR: In patients hospitalized with COVID-19, hydroxychloroquine was not associated with reductions in 28-day mortality but was associated with an increased length of hospital stay and increased risk of progressing to invasive mechanical ventilation or death.
Journal ArticleDOI
Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis.
George Dimopoulos,Quirijn de Mast,Nikolaos Markou,Maria Theodorakopoulou,Apostolos Komnos,Maria Mouktaroudi,Mihai G. Netea,Mihai G. Netea,Themistoklis N. Spyridopoulos,Rebecca J. H. M. Verheggen,Jacobien Hoogerwerf,Alexandra Lachana,Frank L. van de Veerdonk,Evangelos J. Giamarellos-Bourboulis +13 more
TL;DR: The data suggest that administration of Anakinra may be beneficial for treating severe COVID-19 patients with sHLH as determined by the HScore and support the need for larger clinical studies to validate this concept.
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Neurological Involvement in COVID-19 and Potential Mechanisms: A Review.
Ghazal Aghagoli,Benjamin Gallo Marin,Nicole J Katchur,Franz Chaves-Sell,Wael F. Asaad,Sarah Murphy +5 more
TL;DR: A range of clinical observations and initial case series describing potential neurologic manifestations of COVID-19 are synthesized and place these observations in the context of coronavirus neuro-pathophysiology as it may relate to SARS-CoV-2 infection.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
Journal ArticleDOI
Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
Journal ArticleDOI
Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
Christian Drosten,Stephan Günther,Wolfgang Preiser,Sylvie van der Werf,H. R. Brodt,Stephan Becker,Holger F. Rabenau,Marcus Panning,Larissa Kolesnikova,Ron A. M. Fouchier,Annemarie Berger,Ana-Maria Burguière,Jindrich Cinatl,Markus Eickmann,Nicolas Escriou,Klaus Grywna,Stefanie Kramme,Jean-Claude Manuguerra,Stefanie Müller,Volker Rickerts,Martin Stürmer,Simon Vieth,Hans-Dieter Klenk,Albert D. M. E. Osterhaus,Herbert Schmitz,Hans Wilhelm Doerr +25 more
TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
Journal ArticleDOI
Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
Journal ArticleDOI
The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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