Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
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Clinical and pathological investigation of patients with severe COVID-19.
Shaohua Li,Lina Jiang,Xi Li,Fang Lin,Yijin Wang,Boan Li,Tianjun Jiang,Weimin An,Shuhong Liu,Hongyang Liu,Pengfei Xu,Lihua Zhao,Lixin Zhang,Jinsong Mu,Hongwei Wang,Jiarui Kang,Yan Li,Lei Huang,Caizhong Zhu,Shousong Zhao,Jiangyang Lu,Junsheng Ji,Jingmin Zhao +22 more
TL;DR: Circulating cytokines, including IL-8, IL-6, TNF-α, IP10, MCP1, and RANTES, were significantly elevated in patients with severe COVID-19 and could be used to predict disease deterioration and inform clinical interventions.
Journal ArticleDOI
Ocular manifestations and clinical characteristics of 535 cases of COVID-19 in Wuhan, China: a cross-sectional study.
Liwen Chen,Chaohua Deng,Xuhui Chen,Xian Zhang,Bo Chen,Huimin Yu,Yuanjun Qin,Ke Xiao,Hong Zhang,Xufang Sun +9 more
TL;DR: To investigate the ocular manifestations and clinical characteristics of COVID‐19 patients caused by SARS‐CoV‐2 in Wuhan, China, a large number of patients with suspected SARS-related eye problems were admitted to hospital.
Journal ArticleDOI
Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection.
TL;DR: Current evidence is critically examined whether and how the SARS-CoV-2 virus can follow a route from the olfactory epithelium in the nose to the brain to achieve brain infection and the prospects for using the smell and taste dysfunctions seen in COVID-19 as an early and rapid diagnostic screening tool are discussed.
Posted ContentDOI
Correlation Analysis Between Disease Severity and Inflammation-related Parameters in Patients with COVID-19 Pneumonia
Jing Gong,Hui Dong,Qing-Song Xia,Zhaoyi Huang,Dingkun Wang,Yan Zhao,Wen-hua Liu,Shenghao Tu,Mingmin Zhang,Qi Wang,Fuer Lu +10 more
TL;DR: Inflammation is closely related to severity of COVID-19, and IL-6, TNFα andIL-8 might be promising therapeutic targets, and the progress of CO VID-19 to critical stage should be closely observed and possibly prevented.
Journal ArticleDOI
Current epidemiological and clinical features of COVID-19; a global perspective from China.
TL;DR: This review systematically discusses the etiology, epidemiology, clinical characteristics, and current intervention measures related to COVID-19 in the hope that it may provide a reference for future studies and aid in the prevention and control of the CO VID-19 epidemic.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
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TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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Christian Drosten,Stephan Günther,Wolfgang Preiser,Sylvie van der Werf,H. R. Brodt,Stephan Becker,Holger F. Rabenau,Marcus Panning,Larissa Kolesnikova,Ron A. M. Fouchier,Annemarie Berger,Ana-Maria Burguière,Jindrich Cinatl,Markus Eickmann,Nicolas Escriou,Klaus Grywna,Stefanie Kramme,Jean-Claude Manuguerra,Stefanie Müller,Volker Rickerts,Martin Stürmer,Simon Vieth,Hans-Dieter Klenk,Albert D. M. E. Osterhaus,Herbert Schmitz,Hans Wilhelm Doerr +25 more
TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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