Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
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COVID-19 for the Cardiologist: Basic Virology, Epidemiology, Cardiac Manifestations, and Potential Therapeutic Strategies
TL;DR: The virology and potential mechanism of injury form the basis for a discussion of potential disease-modifying therapies, and several mechanisms of injury are proposed with a focus on cardiovascular complications.
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Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists.
TL;DR: This new emergency is a zoonotic disease with unknown animal reservoir and with evidence of person-to-person transmission that involved a novel coronavirus SARS-CoV-2 (aka 2019-nCoV) that involved cases of respiratory illness in humans appearing first in Wuhan, Hubei Province.
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Peptide-like and small-molecule inhibitors against Covid-19.
TL;DR: In-silico approaches are utilized to identify possible protease inhibitors against SARS-CoV-2 and Cobicistat, ritonavir, lopinavir, and darunavir are in the top screened molecules from FDA approved drugs.
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Gastrointestinal Symptoms and Coronavirus Disease 2019: A Case-Control Study From the United States.
Yael R. Nobel,Meaghan Phipps,Jason Zucker,Benjamin Lebwohl,Timothy C. Wang,Magdalena E. Sobieszczyk,Daniel E. Freedberg +6 more
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Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.
Kostas Danis,Olivier Epaulard,Olivier Epaulard,Thomas Bénet,Alexandre Gaymard,Séphora Campoy,Elisabeth Botelho-Nevers,Maude Bouscambert-Duchamp,Guillaume Spaccaferri,Florence Ader,Alexandra Mailles,Zoubida Boudalaa,Violaine Tolsma,Julien Berra,Sophie Vaux,Emmanuel Forestier,Caroline Landelle,Caroline Landelle,Erica Fougere,Alexandra Thabuis,Philippe Berthelot,Raphael Veil,Daniel Lévy-Bruhl,Christian Chidiac,Bruno Lina,Bruno Coignard,C. Saura +26 more
TL;DR: The occurrence in this cluster of one asymptomatic case with similar viral load as a symptomatic patient, suggests transmission potential of asymPTomatic individuals and underscores the need for close monitoring of the clinical evolution of suspect Covid-19 cases.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
Christian Drosten,Stephan Günther,Wolfgang Preiser,Sylvie van der Werf,H. R. Brodt,Stephan Becker,Holger F. Rabenau,Marcus Panning,Larissa Kolesnikova,Ron A. M. Fouchier,Annemarie Berger,Ana-Maria Burguière,Jindrich Cinatl,Markus Eickmann,Nicolas Escriou,Klaus Grywna,Stefanie Kramme,Jean-Claude Manuguerra,Stefanie Müller,Volker Rickerts,Martin Stürmer,Simon Vieth,Hans-Dieter Klenk,Albert D. M. E. Osterhaus,Herbert Schmitz,Hans Wilhelm Doerr +25 more
TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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