Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
Citations
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COVID-19-neutralizing antibodies predict disease severity and survival.
Wilfredo F. Garcia-Beltran,Evan C. Lam,Michael G Astudillo,Diane Yang,Tyler E. Miller,Jared Feldman,Blake M. Hauser,Timothy M. Caradonna,Kiera L. Clayton,Adam Nitido,Mandakolathur R. Murali,Galit Alter,Richelle C. Charles,Anand S. Dighe,John A. Branda,Jochen K. Lennerz,Daniel Lingwood,Aaron G. Schmidt,A. John Iafrate,Alejandro B. Balazs +19 more
TL;DR: It is found that severe cases resulting in intubation or death exhibited increased inflammatory markers, lymphopenia, pro-inflammatory cytokines, and high anti-receptor binding domain (RBD) antibody levels, highlighting the importance of neutralizing humoral immunity on disease progression and the need to develop broadly protective interventions to prevent future coronavirus pandemics.
Journal ArticleDOI
A deep learning algorithm using CT images to screen for Corona virus disease (COVID-19).
Shuai Wang,Bo Kang,Jinlu Ma,Xianjun Zeng,Mingming Xiao,Jia Guo,Mengjiao Cai,Jingyi Yang,Yaodong Li,Xiangfei Meng,Bo Xu,Bo Xu +11 more
TL;DR: In this article, a deep learning algorithm was used to detect the presence of COVID-19 in CT images during the 2015-2016 influenza season, achieving an accuracy of 89.5% with a specificity of 0.88 and sensitivity of 0.87.
Journal ArticleDOI
Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China.
TL;DR: Patients with elder age, chronic comorbidities, blood leukocyte/lymphocyte count, procalcitonin level, co-infection and severe complications might increase the risk of poor clinical outcomes.
Journal ArticleDOI
Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China.
Qingxian Cai,Fengjuan Chen,Tao Wang,Fang Luo,Xiaohui Liu,Qikai Wu,Qing He,Zhaoqin Wang,Yingxia Liu,Lei Liu,Jun Chen,Lin Xu +11 more
TL;DR: In this study, obese patients had increased odds of progressing to severe COVID-19 and clinicians should pay close attention to obese patients, who should be carefully managed with prompt and aggressive treatment.
Journal ArticleDOI
Prevalence of and Risk Factors Associated With Mental Health Symptoms Among the General Population in China During the Coronavirus Disease 2019 Pandemic.
Le Shi,Zheng An Lu,Jian Yu Que,Xiao Lin Huang,Lin Liu,Mao-Sheng Ran,Yi Miao Gong,Yi Miao Gong,Kai Yuan,Wei Yan,Yankun Sun,Jie Shi,Yanping Bao,Lin Lu,Lin Lu +14 more
TL;DR: The mental health burden associated with CO VID-19 is considerable among the general population of China, suggesting that mental health interventions are in urgent demand during the COVID-19 pandemic, especially for some at-risk populations.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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