Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
Citations
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Structural Basis of Potential Inhibitors Targeting SARS-CoV-2 Main Protease
TL;DR: In this article, the structural basis of potential inhibitors targeting SARS-CoV-2 Mpro, identifies gaps, and provides future directions, highlighting compounds with potential Mpro based antiviral activity.
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COVID-19 associated with pulmonary aspergillosis: A literature review.
Chih-Cheng Lai,Weng-Liang Yu +1 more
TL;DR: It is found that Aspergillus spp.
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What dentists need to know about COVID-19.
TL;DR: There is a potentially huge COVID-19 infectious vulnerability risk for oral cavity and brought up a proof for the future prevention procedure in dental practice and daily life as a result of the ACE-2 expressing on oral cavity mucosa.
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Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding.
Yan-Ting Wu,Chen Liu,Lan Dong,Chenjie Zhang,Yang Chen,Jun Liu,Jun Liu,Chen-Chi Duan,Huiyu Zhang,Ben W.J. Mol,Cindy-Lee Dennis,T. Yin,Jing Yang,He-Feng Huang +13 more
TL;DR: To assess whether vaginal secretions and breast milk of women with coronav virus disease 2019 (COVID‐19) contain severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
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SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy.
TL;DR: Interestingly, SARS-CoV-2 infection downregulates ACE2 expression, which may also play a critical pathogenic role in COVID-19, and targeting ACE2/Ang 1-7 axis and blocking ACE2 interaction with the S protein of Sars-Cov-2 to curtail SARV- CoV- 2 infection are becoming very attractive therapeutics potential for treatment and prevention of CO VID-19.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
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TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
Christian Drosten,Stephan Günther,Wolfgang Preiser,Sylvie van der Werf,H. R. Brodt,Stephan Becker,Holger F. Rabenau,Marcus Panning,Larissa Kolesnikova,Ron A. M. Fouchier,Annemarie Berger,Ana-Maria Burguière,Jindrich Cinatl,Markus Eickmann,Nicolas Escriou,Klaus Grywna,Stefanie Kramme,Jean-Claude Manuguerra,Stefanie Müller,Volker Rickerts,Martin Stürmer,Simon Vieth,Hans-Dieter Klenk,Albert D. M. E. Osterhaus,Herbert Schmitz,Hans Wilhelm Doerr +25 more
TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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