Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
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The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?
TL;DR: In this article, the role of pro-inflammatory cytokines (i.e., IL-1β, IL6, IL8, IL17 and TNFα) in SARS-CoV-2 cytokine release syndrome (CRS) was studied.
Journal ArticleDOI
Correlation analysis between disease severity and inflammation-related parameters in patients with COVID-19: a retrospective study.
Jing Gong,Hui Dong,Qing-Song Xia,Zhaoyi Huang,Dingkun Wang,Yan Zhao,Wen-hua Liu,Shenghao Tu,Mingmin Zhang,Qi Wang,Fuer Lu +10 more
TL;DR: Wang et al. as discussed by the authors analyzed blood inflammation indicators among mild, severe and critical patients, helping to identify severe or critical patients early, and found that inflammatory concerns on disease progression are closely related to severity of COVID-19, and IL-6 and TNFα might be promising therapeutic targets.
Journal ArticleDOI
COVID-19 pandemic: A pragmatic plan for ayurveda intervention.
TL;DR: Drawing on the Ayurveda classics, contemporary scientific studies, and experiential knowledge on similar clinical settings, a pragmatic plan for intervention in India is proposed for graded response, depending on the stage of infection among individuals, in a population.
Journal ArticleDOI
Coping style, social support and psychological distress in the general Chinese population in the early stages of the COVID-19 epidemic.
TL;DR: The COVID-19 outbreak in China has a great impact on the mental health status of the general population, and active coping strategies and increased social support are significantly correlated with decreased psychological distress, and may serve as the basis for psychological interventions.
Journal ArticleDOI
COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2).
TL;DR: Key evidence from in vitro researches, animal models and clinical researches in emerging coronaviruses are examined and Xuebijing may benefit patients with complications of bacterial pneumonia or sepsis and the efficacy of interferon is unclear.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
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TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
Christian Drosten,Stephan Günther,Wolfgang Preiser,Sylvie van der Werf,H. R. Brodt,Stephan Becker,Holger F. Rabenau,Marcus Panning,Larissa Kolesnikova,Ron A. M. Fouchier,Annemarie Berger,Ana-Maria Burguière,Jindrich Cinatl,Markus Eickmann,Nicolas Escriou,Klaus Grywna,Stefanie Kramme,Jean-Claude Manuguerra,Stefanie Müller,Volker Rickerts,Martin Stürmer,Simon Vieth,Hans-Dieter Klenk,Albert D. M. E. Osterhaus,Herbert Schmitz,Hans Wilhelm Doerr +25 more
TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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