Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.About:
This article is published in The Lancet.The article was published on 2020-01-30 and is currently open access. It has received 16282 citations till now.read more
Citations
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COVID-19 associated pulmonary aspergillosis (CAPA)—from immunology to treatment
Amir Arastehfar,Agostinho Carvalho,Frank L. van de Veerdonk,Jeffrey D. Jenks,Philipp Koehler,Robert Krause,Oliver A. Cornely,David S. Perlin,Cornelia Lass-Flörl,Martin Hoenigl +9 more
TL;DR: The treatment of CAPA is complicated by drug–drug interactions associated with broad spectrum azoles, renal tropism and damage caused by SARS-CoV-2, which may challenge the use of liposomal amphotericin B, as well as the emergence of azole-resistance.
Journal ArticleDOI
ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19.
Bruna G G Pinto,Antonio E R Oliveira,Youvika Singh,Leandro Jimenez,Andre N A Gonçalves,Rodrigo L T Ogava,Rachel Creighton,Jean Pierre Schatzmann Peron,Helder I. Nakaya +8 more
TL;DR: It is found that ACE2 was highly expressed in these patients, compared to control individuals, and this finding suggests that patients with such comorbidities may have higher chances of developing severe COVID-19.
Journal ArticleDOI
Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2: A systematic review and meta-analysis.
TL;DR: COVID‐19 is a new clinical infectious disease that mainly causes bilateral pneumonia and lung function deteriorates rapidly, and patients are likely to present respiratory failure or even death.
Journal ArticleDOI
COVID-19-Associated Kidney Injury: A Case Series of Kidney Biopsy Findings.
Purva Sharma,Nupur N. Uppal,Rimda Wanchoo,Hitesh H. Shah,Yihe Yang,Rushang Parikh,Yuriy Khanin,Varun Madireddy,Christopher P. Larsen,Kenar D. Jhaveri,Vanesa Bijol +10 more
TL;DR: The most common finding in kidney biopsy samples from ten hospitalized patients with AKI and COVID-19 was acute tubular necrosis, and there was no evidence of SARS-CoV-2 in the biopsied kidney tissue.
Journal ArticleDOI
Association of Sex, Age, and Comorbidities with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis.
TL;DR: Implementing adequate protection and interventions for COVID-19 patients in general and in particular male patients with age ≥50 years having comorbidities may significantly reduce risk of mortality associated with CO VID-19.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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TL;DR: The novel coronavirus might have a role in causing SARS and was detected in a variety of clinical specimens from patients with SARS but not in controls.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S.C. Hui,Esam Ei Azhar,Tariq A. Madani,Francine Ntoumi,Richard Kock,Osman Dar,Giuseppe Ippolito,Timothy D. McHugh,Ziad A. Memish,Christian Drosten,Alimuddin Zumla,Eskild Petersen +11 more
TL;DR: The recent outbreak of clusters of viral pneumonia due to a 2019-nCoV in the Wuhan market poses significant threats to international health and may be related to sale of bush meat derived from wild or captive sources at the seafood market.
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