First Description of SARS-CoV-2 Infection in Two Feral American Mink (Neovison vison) Caught in the Wild.
Jordi Aguiló-Gisbert,Miguel Padilla-Blanco,Victor Lizana,Elisa Maiques,Marta Muñoz-Baquero,Eva Chillida-Martínez,Jesús Cardells,Consuelo Rubio-Guerri +7 more
TLDR
In this article, the authors reported the detection of SARS-CoV-2 in 2 of 13 American mink (Neovison vison) trapped in the Valencian Community (Eastern Spain), during an invasive species trapping campaign.Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, is considered a pathogen of animal origin that is mainly transmitted from human to human. Several animal species can be naturally or experimentally infected by SARS-CoV-2, with compelling evidence that mink is highly susceptible to SARS-CoV-2 infection. Human-to-mink infection cases have been reported and there are also suggestions that mink-to-human infection occurs. Mink infections have been reported to date only on fur farms, except for one infected free- ranging wild mink near a Utah (USA) fur farm, which suggests a transmission pathway from farms to wild mink. We now report the detection of SARS-CoV-2 in 2 of 13 feral dark brown American mink (Neovison vison) trapped in the Valencian Community (Eastern Spain), during an invasive species trapping campaign. They were trapped in riverbeds in sparsely inhabited rural areas known to harbor self-sustained feral mink populations. The closest fur farm is about 20 km away. SARS-CoV-2 RNA was detected by two-step RT-PCR in these animals' mesenteric lymph nodes and was confirmed by sequencing a 397-nucleotide amplified region of the S gene, yielding identical sequences in both animals. A molecular phylogenetic analysis was run on this sequence, which was found to correspond to the consensus SARS-CoV-2 sequence from Wuhan. Our findings appear to represent the first example of SARS-CoV-2 acquired in the wild by feral mink in self-sustained populations.read more
Citations
More filters
Journal ArticleDOI
Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and associated humans in the Netherlands.
Lu Lu,Reina S. Sikkema,Francisca C. Velkers,David F. Nieuwenhuijse,Egil A.J. Fischer,Paola A. Meijer,Noortje Bouwmeester-Vincken,Ariene Rietveld,M. C. A. Wegdam-Blans,Paulien Tolsma,Marco Koppelman,Lidwien A.M. Smit,Renate W. Hakze-van der Honing,Wim H.M. van der Poel,Arco N. van der Spek,Marcel A.H. Spierenburg,Robert Jan Molenaar,Jan de Rond,Marieke Augustijn,Mark E. J. Woolhouse,J. Arjan Stegeman,Samantha Lycett,Bas B. Oude Munnink,Marion Koopmans +23 more
TL;DR: In this article, the first wave of the COVID-19 pandemic (April 2020) was detected in farmed minks and genomic sequencing was performed on mink farms and farm personnel.
Journal ArticleDOI
Natural and Experimental SARS-CoV-2 Infection in Domestic and Wild Animals.
TL;DR: In this paper, the authors summarized the current findings regarding the susceptibility of different domestic and wild animal species to experimental SARS-CoV-2 infection and provided detailed descriptions of the clinical disease and transmissibility in these animals.
Posted ContentDOI
First detection of SARS-CoV-2 infection in Canadian wildlife identified in free-ranging white-tailed deer (Odocoileus virginianus) from southern Québec, Canada
Jonathon D. Kotwa,Ariane Massé,Marianne Gagnier,Patryk Aftanas,Juliette Blais-Savoie,Jeff Bowman,Tore Buchanan,Hsien-Yao Chee,Antonia Dibernardo,Peter Kruczkiewicz,K. Nirmalarajah,Catherine Soos,Lily Yip,L. R. Lindsay,Oliver Lung,Brad S. Pickering,Samira Mubareka +16 more
TL;DR: Investigation of SARS-CoV-2 infection in white-tailed deer in Québec, Canada found mutations in the S-gene and a deletion in ORF8 encoding a truncated protein were detected; evidence of past exposure was detected among deer from the same region.
Journal ArticleDOI
Assessing the risk of human‐to‐wildlife pathogen transmission for conservation and public health
Anna C. Fagre,Lily E. Cohen,Evan A. Eskew,Maxwell J. Farrell,Emma E. Glennon,Maxwell B. Joseph,Hannah K. Frank,Sadie J. Ryan,Colin J. Carlson,Gregory F. Albery +9 more
TL;DR: In this article , the authors reviewed published evidence of human-to-wildlife transmission events, with a focus on how such events could threaten animal and human health, and identified 97 verified examples, involving a wide range of pathogens; however, reported hosts were mostly nonhuman primates or large, long-lived captive animals.
Journal ArticleDOI
Evolutionary Dynamics and Epidemiology of Endemic and Emerging Coronaviruses in Humans, Domestic Animals, and Wildlife.
Ariful Islam,Ariful Islam,Jinnat Ferdous,Jinnat Ferdous,Shariful Islam,Abu Sayeed,Shusmita Dutta Choudhury,Otun Saha,Mohammad Mahmudul Hassan,Tahmina Shirin +9 more
TL;DR: In this paper, the emergence and evolution of endemic and emerging CoV diversity in humans and animals is studied and a universal CoV vaccine for humans is proposed to prevent any future outbreak can be prevented effectively.
References
More filters
Journal ArticleDOI
Bioedit: a user-friendly biological sequence alignment editor and analysis program for windows 95/98/ nt
Journal ArticleDOI
MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms.
TL;DR: The Molecular Evolutionary Genetics Analysis (Mega) software implements many analytical methods and tools for phylogenomics and phylomedicine and has additionally been upgraded to use multiple computing cores for many molecular evolutionary analyses.
Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses
Muhammad Adnan Shereen,Muhammad Adnan Shereen,Suliman Khan,Abeer Kazmi,Nadia Bashir,Rabeea Siddique +5 more
TL;DR: The approaches for developing effective vaccines and therapeutic combinations to cope with this viral outbreak are discussed and the emergence and pathogenicity of COVID-19 infection and previous human coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory virus (MERS- coV) is analyzed.
Journal ArticleDOI
Real-time PCR for mRNA quantitation.
Marisa L. Wong,Juan F. Medrano +1 more
TL;DR: This review discusses the key components of a real-time PCR experiment, including one-step or two-step PCR, absolute versus relative quantitation, mathematical models available for Relative quantitation and amplification efficiency calculations, types of normalization or data correction, and detection chemistries.
Related Papers (5)
Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans.
Bas B. Oude Munnink,Reina S. Sikkema,David F. Nieuwenhuijse,Robert Jan Molenaar,Emmanuelle Munger,Richard Molenkamp,Arco N. van der Spek,Paulien Tolsma,Ariene Rietveld,Miranda Brouwer,Noortje Bouwmeester-Vincken,Frank Harders,Renate Hakze-van der Honing,Marjolein C.A. Wegdam-Blans,Ruth Bouwstra,Corine H. GeurtsvanKessel,Annemiek A. van der Eijk,Francisca C. Velkers,Lidwien A.M. Smit,Arjan Stegeman,Wim H.M. van der Poel,Marion Koopmans +21 more
Infection and Rapid Transmission of SARS-CoV-2 in Ferrets.
Young-Il Kim,Seong Gyu Kim,Se Mi Kim,Eun-Ha Kim,Su-Jin Park,Kwang-Min Yu,Jae Hyung Chang,Eun Ji Kim,Seung-Hun Lee,Mark Anthony B. Casel,Jihye Um,Min-Suk Song,Hye Won Jeong,Van Dam Lai,Yeonjae Kim,Bum Sik Chin,Jun Sun Park,Ki Hyun Chung,Suan-Sin Foo,Haryoung Poo,In Pil Mo,Ok Jun Lee,Richard J. Webby,Jae U. Jung,Young Ki Choi +24 more
SARS-CoV-2 infection in cats and dogs in infected mink farms.
Anna E. van Aart,Francisca C. Velkers,Egil A.J. Fischer,Els M. Broens,Herman Egberink,Shan Zhao,Marc Y. Engelsma,Renate Hakze-van der Honing,Frank Harders,Myrna M.T. de Rooij,Carien Radstake,Paola A. Meijer,Bas B. Oude Munnink,Jan de Rond,Reina S. Sikkema,Arco N. van der Spek,Marcel A.H. Spierenburg,Wendy J. Wolters,Robert Jan Molenaar,Marion Koopmans,Wim H.M. van der Poel,Arjan Stegeman,Lidwien A.M. Smit +22 more