Journal ArticleDOI
Idiopathic multicentric Castleman's disease: a systematic literature review
Amy Y. Liu,Christopher S. Nabel,Brian S. Finkelman,Jason R. Ruth,Razelle Kurzrock,Frits van Rhee,Vera P. Krymskaya,Dermot Kelleher,Arthur H. Rubenstein,David C. Fajgenbaum +9 more
TLDR
A systematic review provides comprehensive information about clinical features, treatment, and outcomes of idiopathic multicentric Castleman's disease, which accounts for at least 33% of all cases of multicentric Castellan's disease.About:
This article is published in The Lancet Haematology.The article was published on 2016-04-01. It has received 198 citations till now.read more
Citations
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Interleukin-6: designing specific therapeutics for a complex cytokine
TL;DR: The roles of IL-6 in health and disease are overviewed and progress with several approaches of inhibitingIL-6-signalling is analyzed, with the aim of illuminating when and how to apply IL- 6 blockade.
Journal ArticleDOI
International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease
David C. Fajgenbaum,Thomas S. Uldrick,Adam Bagg,Dale Frank,David Wu,Gordan Srkalovic,David Simpson,Amy Y. Liu,David M. Menke,Shanmuganathan Chandrakasan,Mary Jo Lechowicz,Raymond S.M. Wong,Sheila K Pierson,Michele Paessler,Jean François Rossi,Makoto Ide,Jason R. Ruth,Michael P. Croglio,Alexander Suarez,Vera P. Krymskaya,Amy Chadburn,Gisele W. B. Colleoni,Sunita D. Nasta,Raj Jayanthan,Christopher S. Nabel,Corey Casper,Angela Dispenzieri,Alexander Fosså,Dermot Kelleher,Razelle Kurzrock,Peter M. Voorhees,Ahmet Dogan,Kazuyuki Yoshizaki,Frits van Rhee,Eric Oksenhendler,Elaine S. Jaffe,Kojo S.J. Elenitoba-Johnson,Megan S. Lim +37 more
TL;DR: The proposed consensus criteria will facilitate consistent diagnosis, appropriate treatment, and collaborative research and exclude infectious, malignant, and autoimmune disorders that can mimic iMCD.
Journal ArticleDOI
International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease
Frits van Rhee,Peter M. Voorhees,Angela Dispenzieri,Alexander Fosså,Gordan Srkalovic,Makoto Ide,Nikhil C. Munshi,Stephen Schey,Matthew Streetly,Sheila K Pierson,Helen L. Partridge,Sudipto Mukherjee,Dustin Shilling,Katie L. Stone,Amy D Greenway,Jason R. Ruth,Mary Jo Lechowicz,Shanmuganathan Chandrakasan,Raj Jayanthan,Elaine S. Jaffe,Heather A. Leitch,Naveen Pemmaraju,Amy Chadburn,Megan S. Lim,Kojo S.J. Elenitoba-Johnson,Vera P. Krymskaya,Aaron M. Goodman,Christian Hoffmann,Pier Luigi Zinzani,Simone Ferrero,Louis Terriou,Yasuharu Sato,David Simpson,Raymond S.M. Wong,Jean François Rossi,Sunita D. Nasta,Kazuyuki Yoshizaki,Razelle Kurzrock,Thomas S. Uldrick,Corey Casper,Eric Oksenhendler,David C. Fajgenbaum +41 more
TL;DR: These guidelines should help treating physicians to stratify patients based on disease severity in order to select the best available therapeutic option to improve outcomes.
Journal ArticleDOI
Overview of Castleman disease.
TL;DR: Advances in diagnosis, classification, pathogenesis, and therapy are substantial since the original description of UCD by Benjamin Castleman in 1954, and further progress will be made by continued engagement of physicians, scientists, and patients.
Journal ArticleDOI
Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes.
James T. England,Alym Abdulla,Catherine M. Biggs,Agnes Y.Y. Lee,Kevin A. Hay,Ryan L. Hoiland,Cheryl L. Wellington,Mypinder S. Sekhon,Shahin Jamal,Kamran Shojania,Luke Y.C. Chen +10 more
TL;DR: Established markers of inflammation as well as cytokine levels are compared and contrasted between these four entities in order to establish a foundation for future diagnostic criteria of COVID-CSS.
References
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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
Yuan Chang,Ethel Cesarman,Melissa S. Pessin,Frank Lee,Janice Culpepper,Daniel M. Knowles,Patrick S. Moore +6 more
TL;DR: unique sequences present in more than 90 percent of Kaposi's sarcoma tissues obtained from patients with acquired immunodeficiency syndrome (AIDS) appear to define a new human herpesvirus.
Journal ArticleDOI
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
Jean Soulier,Laurence Grollet,Eric Oksenhendler,Patrice Cacoub,Dominique Cazals-Hatem,Paul Babinet,Marie-Françoise D'Agay,Jean-Pierre Clauvel,Marline Raphael,Laurent Degos,François Sigaux +10 more
TL;DR: Data suggest that KSHV could play a role in the pathogenesis of MCD, especially in HIV-infected patients, which is a close association with Kaposi's sarcoma.
Journal ArticleDOI
Localized mediastinal lymph‐node hyperplasia resembling thymoma
Journal ArticleDOI
Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV
TL;DR: Four virus proteins similar to two human macrophage inflammatory protein (MIP) chemokines, interleukin-6 (IL-6), and interferon regulatory factor (IRF) are encoded by the Kaposi's sarcoma-associated herpesvirus (KSHV) genome.
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