Improved Noninvasive prediction of Liver Fibrosis by Liver Stiffness Measurement in Patients with Nonalcoholic Fatty Liver Disease Accounting for Controlled Attenuation Parameter Values
Salvatore Petta,Vincent Wai-Sun Wong,Calogero Cammà,Jean-Baptiste Hiriart,Grace Lai-Hung Wong,Fabio Marra,Julien Vergniol,Anthony W.H. Chan,Vito Di Marco,Wassil Merrouche,Henry Lik-Yuen Chan,Marco Barbara,Brigitte Le-Bail,Umberto Arena,Antonio Craxì,Victor de Ledinghen +15 more
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TLDR
In patients with NAFLD, CAP values should always be taken into account in order to avoid overestimations of liver fibrosis assessed by transient elastography.About:
This article is published in Hepatology.The article was published on 2017-04-01 and is currently open access. It has received 168 citations till now. The article focuses on the topics: Nonalcoholic fatty liver disease.read more
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Utility of Fibroscan XL to assess the severity of non-alcoholic fatty liver disease in patients undergoing bariatric surgery.
Andrew C. Yang,Andrew C. Yang,Melinda Nguyen,Irene Ju,Irene Ju,Anthony Brancatisano,Brendan Ryan,David van der Poorten,David van der Poorten +8 more
TL;DR: Fibroscan was successful in 167 (88%) at baseline and 100% at follow-up patients with a failed fibroscan had higher body mass index (BMI) and alanine transaminase (ALT), but no difference in FIB-4/NAFLD score.
Journal ArticleDOI
Transient Elastography in Alcoholic Liver Disease and Nonalcoholic Fatty Liver Disease: A Systemic Review and Meta-Analysis
TL;DR: In this article, the authors investigated the accuracy of transient elastography (TE) for diagnosing steatosis and fibrosis in ALD/NAFLD patients, and the pooled results revealed that the sensitivity and specificity of TE were 0.84, 0.83, and 0.71, respectively.
Journal ArticleDOI
Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity
Alessandra Scamporrino,S. Di Mauro,S. Petta,Francesca Urbano,Agnese Rita Fillippa Tindara Filippello,Maria Alessandra Ragusa,M T Di Martino,Francesca Scionti,Stefania Grimaudo,Rosaria Maria Pipitone,G. Privitera,A. Di Pino,Roberto Scicali,Agata Maria Rabuazzo,Antonio Craxì,Michele Purrello,Francesco Purrello,Salvatore Piro +17 more
TL;DR: The cast of the 70th Venice International Film Festival is revealed, with a focus on the visually impaired and those with special needs.
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Comparative Utility of Transient and 2D Shear Wave Elastography for the Assessment of Liver Fibrosis in Clinical Practice.
Dimitrios Karagiannakis,Theodoros Voulgaris,Theodoros Angelopoulos,Panagiota Ioannidou,Evangelos Cholongitas,Jiannis Vlachogiannakos,George V. Papatheodoridis +6 more
TL;DR: In this article, the feasibility and correlation of liver stiffness measurements (LSM) between 2D-shear wave elastography (2D-SWE) and TE (M and/or XL probe) in patients with chronic liver disease was investigated.
Journal ArticleDOI
The liver steatosis severity and lipid characteristics in primary biliary cholangitis.
Yuan Zhang,Xing Hu,Jing Chang,Jie Chen,Xue Han,Tieying Zhang,Jianjun Shen,Ning Shang,Jing Han,Hui Wang,Weiwei Kang,Fankun Meng +11 more
TL;DR: In this article, the authors analyzed the characteristics of lipid distribution and the degree of hepatic steatosis in primary biliary cholangitis (PBC) patients and found that among the five groups of subjects, the PBC group had the lowest CAP values.
References
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Design and validation of a histological scoring system for nonalcoholic fatty liver disease
David E. Kleiner,Elizabeth M. Brunt,Mark L. Van Natta,Cynthia Behling,Melissa J. Contos,Oscar W. Cummings,Linda D. Ferrell,Yao Chang Liu,Michael Torbenson,Aynur Unalp-Arida,Matthew M. Yeh,Arthur J. McCullough,Arun J. Sanyal +12 more
TL;DR: A strong scoring system and NAS for NAFLD and NASH with reasonable inter‐rater reproducibility that should be useful for studies of both adults and children with any degree ofNAFLD are presented.
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Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes
Zobair M. Younossi,Zobair M. Younossi,Aaron B. Koenig,Dinan Abdelatif,Yousef Fazel,Linda Henry,Mark Wymer,Mark Wymer +7 more
TL;DR: As the global epidemic of obesity fuels metabolic conditions, the clinical and economic burden of NAFLD will become enormous, and random‐effects models were used to provide point estimates of prevalence, incidence, mortality and incidence rate ratios.
Journal ArticleDOI
EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease
Giulio Marchesini,Christopher P. Day,Jean-François Dufour,Ali Canbay,Valerio Nobili,Vlad Ratziu,Herbert Tilg,Michael Roden,Amalia Gastaldelli,Hannele Yki-Järvinen,Fritz Schick,Roberto Vettor,Gema Frühbeck,Lisbeth Mathus-Vliegen +13 more
TL;DR: The final purpose is to improve patient care and awareness of the importance of NAFLD, and to assist stakeholders in the decision-making process by providing evidence-based data, which also takes into consideration the burden of clinical management for the healthcare system.
Journal ArticleDOI
The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD
Paul Angulo,Jason M. Hui,Giulio Marchesini,Ellisabetta Bugianesi,Jacob George,Geoffrey C. Farrell,Felicity Enders,Sushma Saksena,Alastair D. Burt,John P. Bida,Keith D. Lindor,Schuyler O. Sanderson,Marco Lenzi,Leon A. Adams,James G. Kench,Terry M. Therneau,Christopher P. Day +16 more
TL;DR: A simple scoring system accurately separates patients with nonalcoholic fatty liver disease with and without advanced fibrosis, rendering liver biopsy for identification ofAdvanced fibrosis unnecessary in a substantial proportion of patients.
Journal ArticleDOI
Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
Paul Angulo,David E. Kleiner,Sanne Dam-Larsen,Leon A. Adams,Einar Björnsson,Phunchai Charatcharoenwitthaya,Peter R. Mills,Jill C. Keach,Heather D. Lafferty,Alisha C. Stahler,Svanhildur Haflidadottir,Flemming Bendtsen +11 more
TL;DR: In a longitudinal study of patients with NAFLD, fibrosis stage, but no other histologic features of steatohepatitis, were associated independently with long-term overall mortality, liver transplantation, and liver-related events.