Improved Noninvasive prediction of Liver Fibrosis by Liver Stiffness Measurement in Patients with Nonalcoholic Fatty Liver Disease Accounting for Controlled Attenuation Parameter Values
Salvatore Petta,Vincent Wai-Sun Wong,Calogero Cammà,Jean-Baptiste Hiriart,Grace Lai-Hung Wong,Fabio Marra,Julien Vergniol,Anthony W.H. Chan,Vito Di Marco,Wassil Merrouche,Henry Lik-Yuen Chan,Marco Barbara,Brigitte Le-Bail,Umberto Arena,Antonio Craxì,Victor de Ledinghen +15 more
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TLDR
In patients with NAFLD, CAP values should always be taken into account in order to avoid overestimations of liver fibrosis assessed by transient elastography.About:
This article is published in Hepatology.The article was published on 2017-04-01 and is currently open access. It has received 168 citations till now. The article focuses on the topics: Nonalcoholic fatty liver disease.read more
Citations
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Journal ArticleDOI
Impact of controlled attenuation parameter on detecting fibrosis using liver stiffness measurement
Thomas Karlas,David Petroff,Magali Sasso,Jian-Gao Fan,Y. Q. Mi,V. de Ledinghen,Maneesh Kumar,Monica Lupsor-Platon,Kwang Hyub Han,A.C. Cardoso,Giovanna Ferraioli,Wah-Kheong Chan,Vincent Wai-Sun Wong,R. Myers,Kazuaki Chayama,Mireen Friedrich-Rust,Michel Beaugrand,Feng Shen,Jean-Baptiste Hiriart,Shiv Kumar Sarin,Radu Badea,H. W. Lee,Patrick Marcellin,Carlo Filice,Sanjiv Mahadeva,Grace Lai-Hung Wong,Pam Crotty,Keiichi Masaki,Jörg Bojunga,P. Bedossa,Volker Keim,Johannes Wiegand +31 more
TL;DR: Control Attenuation Parameter (CAP) added to transient elastography enables simultaneous assessment of steatosis and fibrosis in patients with non‐alcoholic fatty liver disease.
Journal ArticleDOI
Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
Maud Lemoine,Lambert Assoumou,Stéphane De Wit,Pierre-Marie Girard,Marc Antoine Valantin,Christine Katlama,Coca Valentina Necsoi,Pauline Campa,Anja D Huefner,Julian Schulze zur Wiesch,Hayette Rougier,Jean-Philippe Bastard,Hartmut Stocker,Stefan Mauss,Lawrence Serfaty,Vlad Ratziu,Yves Menu,Jerome Schlue,Georg M. N. Behrens,Pierre Bedossa,Jacqueline Capeau,Patrick Ingiliz,Dominique Costagliola +22 more
TL;DR: Using liver biopsy (LB) as a reference, the authors assessed the accuracy of non-invasiv tests of steatosis, non-alcoholic steatohepatitis (NASH), and fibrosis.
Journal ArticleDOI
Steatosis severity affects the diagnostic performances of noninvasive fibrosis tests in nonalcoholic fatty liver disease.
Sae Kyung Joo,Won Kim,Donghee Kim,Jung Ho Kim,Sohee Oh,Kook Lae Lee,Mee Soo Chang,Yong Jin Jung,Young So,Myoung Seok Lee,Jeong Mo Bae,Byeong Gwan Kim +11 more
TL;DR: The diagnostic performances of noninvasive fibrosis tests in predicting advanced fibrosis among patients with NAFLD are compared and the effects of the subgroups on their diagnostic performances are examined.
Journal ArticleDOI
A Critical Appraisal of the Use of Ultrasound in Hepatic Steatosis
TL;DR: This review highlights the recent developments in the use of ultrasound-based techniques in NAFLD and their performance in predicting metabolic derangements, cardiovascular risk, and progression of liver disease, notably including diagnosis of fibrosing NASH, identification, and treatment of HCC.
Journal ArticleDOI
Liver stiffness does not affect ultrasound-guided attenuation coefficient measurement in the evaluation of hepatic steatosis.
Toshifumi Tada,Takashi Kumada,Hidenori Toyoda,Satoshi Yasuda,Yashuhiro Sone,Shinichi Hashinokuchi,Sadanobu Ogawa,Takuma Oguri,Naohisa Kamiyama,Makoto Chuma,Tomoyuki Akita,Junko Tanaka +11 more
TL;DR: This work investigated whether fibrosis identified by hepatic stiffness measurements based on magnetic resonance elastography (MRE) affects attenuation coefficient measurement using UGAP for the evaluation of hepatic steatosis.
References
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Design and validation of a histological scoring system for nonalcoholic fatty liver disease
David E. Kleiner,Elizabeth M. Brunt,Mark L. Van Natta,Cynthia Behling,Melissa J. Contos,Oscar W. Cummings,Linda D. Ferrell,Yao Chang Liu,Michael Torbenson,Aynur Unalp-Arida,Matthew M. Yeh,Arthur J. McCullough,Arun J. Sanyal +12 more
TL;DR: A strong scoring system and NAS for NAFLD and NASH with reasonable inter‐rater reproducibility that should be useful for studies of both adults and children with any degree ofNAFLD are presented.
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Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes
Zobair M. Younossi,Zobair M. Younossi,Aaron B. Koenig,Dinan Abdelatif,Yousef Fazel,Linda Henry,Mark Wymer,Mark Wymer +7 more
TL;DR: As the global epidemic of obesity fuels metabolic conditions, the clinical and economic burden of NAFLD will become enormous, and random‐effects models were used to provide point estimates of prevalence, incidence, mortality and incidence rate ratios.
Journal ArticleDOI
EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease
Giulio Marchesini,Christopher P. Day,Jean-François Dufour,Ali Canbay,Valerio Nobili,Vlad Ratziu,Herbert Tilg,Michael Roden,Amalia Gastaldelli,Hannele Yki-Järvinen,Fritz Schick,Roberto Vettor,Gema Frühbeck,Lisbeth Mathus-Vliegen +13 more
TL;DR: The final purpose is to improve patient care and awareness of the importance of NAFLD, and to assist stakeholders in the decision-making process by providing evidence-based data, which also takes into consideration the burden of clinical management for the healthcare system.
Journal ArticleDOI
The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD
Paul Angulo,Jason M. Hui,Giulio Marchesini,Ellisabetta Bugianesi,Jacob George,Geoffrey C. Farrell,Felicity Enders,Sushma Saksena,Alastair D. Burt,John P. Bida,Keith D. Lindor,Schuyler O. Sanderson,Marco Lenzi,Leon A. Adams,James G. Kench,Terry M. Therneau,Christopher P. Day +16 more
TL;DR: A simple scoring system accurately separates patients with nonalcoholic fatty liver disease with and without advanced fibrosis, rendering liver biopsy for identification ofAdvanced fibrosis unnecessary in a substantial proportion of patients.
Journal ArticleDOI
Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
Paul Angulo,David E. Kleiner,Sanne Dam-Larsen,Leon A. Adams,Einar Björnsson,Phunchai Charatcharoenwitthaya,Peter R. Mills,Jill C. Keach,Heather D. Lafferty,Alisha C. Stahler,Svanhildur Haflidadottir,Flemming Bendtsen +11 more
TL;DR: In a longitudinal study of patients with NAFLD, fibrosis stage, but no other histologic features of steatohepatitis, were associated independently with long-term overall mortality, liver transplantation, and liver-related events.