Individualizing Risk Prediction for Positive Coronavirus Disease 2019 Testing: Results From 11,672 Patients.
Lara Jehi,Xinge Ji,Alex Milinovich,Serpil C. Erzurum,Brian P. Rubin,Steve Gordon,James B. Young,Michael W. Kattan +7 more
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TLDR
Relevance of age, race, gender, and socioeconomic characteristics in COVID-19-susceptibility is demonstrated and a potential modifying role of certain common vaccinations and drugs identified in drug-repurposing studies is suggested.Citations
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future.
Journal ArticleDOI
Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal
Laure Wynants,Laure Wynants,Ben Van Calster,Ben Van Calster,Gary S. Collins,Gary S. Collins,Richard D Riley,Georg Heinze,Ewoud Schuit,Marc J.M. Bonten,Darren Dahly,Johanna A A G Damen,Thomas P. A. Debray,Valentijn M.T. de Jong,Maarten De Vos,Paula Dhiman,Paula Dhiman,Maria C Haller,Michael O. Harhay,Liesbet Henckaerts,Pauline Heus,Michael Kammer,Nina Kreuzberger,Anna Lohmann,Kim Luijken,Jie Ma,Glen P. Martin,David J. McLernon,Constanza L Andaur Navarro,Johannes B. Reitsma,Jamie C. Sergeant,Chunhu Shi,Nicole Skoetz,Luc J.M. Smits,Kym I E Snell,Matthew Sperrin,René Spijker,René Spijker,Ewout W. Steyerberg,Toshihiko Takada,Ioanna Tzoulaki,Ioanna Tzoulaki,Sander M. J. van Kuijk,Bas C T van Bussel,Bas C T van Bussel,Iwan C. C. van der Horst,Florien S. van Royen,Jan Y Verbakel,Jan Y Verbakel,Christine Wallisch,Christine Wallisch,Jack Wilkinson,Robert Wolff,Lotty Hooft,Karel G.M. Moons,Maarten van Smeden +55 more
TL;DR: Proposed models for covid-19 are poorly reported, at high risk of bias, and their reported performance is probably optimistic, according to a review of published and preprint reports.
Journal ArticleDOI
Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US
Shruti Gupta,Salim S. Hayek,Wei Wang,Lili Chan,Kusum S. Mathews,Michal L. Melamed,Samantha K. Brenner,Amanda K. Leonberg-Yoo,Edward J. Schenck,Jared Radbel,Jochen Reiser,Anip Bansal,Anand Srivastava,Yan Zhou,Anne Sutherland,Adam E. Green,Alexandre M. Shehata,Nitender Goyal,Anitha Vijayan,Juan Carlos Q. Velez,Juan Carlos Q. Velez,Shahzad Shaefi,Chirag R. Parikh,Justin Arunthamakun,Ambarish M. Athavale,Allon N. Friedman,Samuel A.P. Short,Zoe A. Kibbelaar,Samah Abu Omar,Andrew J Admon,John P. Donnelly,Hayley B. Gershengorn,Hayley B. Gershengorn,Miguel A. Hernán,Miguel A. Hernán,Matthew W. Semler,David E. Leaf +36 more
TL;DR: This study identified demographic, clinical, and hospital-level risk factors that may be associated with death in critically ill patients with COVID-19 and can facilitate the identification of medications and supportive therapies to improve outcomes.
Journal ArticleDOI
Racial and Ethnic Disparities in COVID-19-Related Infections, Hospitalizations, and Deaths : A Systematic Review.
Katherine Mackey,Chelsea Ayers,Karli Kondo,Somnath Saha,Shailesh Advani,Sarah Young,Hunter C. Spencer,Max Rusek,Johanna Anderson,Stephanie Veazie,Mia Smith,Devan Kansagara +11 more
TL;DR: A systematic review evaluating racial/ethnic disparities in SARS-CoV-2 infection rates and COVID-19 outcomes, factors contributing to disparities, and interventions to reduce them suggests that impacts of CO VID-19 differ among U.S. racial/ ethnic groups.
Disparities in COVID-19 Outcomes by Race, Ethnicity, and Socioeconomic Status: A Systematic-Review and Meta-analysis.
Shruti Magesh,Shruti Magesh,Daniel John,Daniel John,Wei Tse Li,Wei Tse Li,Yuxiang Li,Yuxiang Li,Aidan Mattingly-App,Aidan Mattingly-App,Sharad Jain,Eric Y. Chang,Eric Y. Chang,Weg M. Ongkeko,Weg M. Ongkeko +14 more
TL;DR: In this article, the authors evaluated the association of race and ethnicity with COVID-19 outcomes and examined the association between race, ethnicity, COVID19 outcomes, and socioeconomic determinants.
References
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Journal ArticleDOI
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
Chaomin Wu,Xiaoyan Chen,Yanping Cai,Jia’an Xia,Xing Zhou,Sha Xu,Han-Ping Huang,Li Zhang,Xia Zhou,Chunling Du,Yuye Zhang,Juan Song,Sijiao Wang,Yencheng Chao,Zeyong Yang,Jie Xu,Xin Zhou,Dechang Chen,Weining Xiong,Lei Xu,Feng Zhou,Jinjun Jiang,Chunxue Bai,Zheng Junhua,Yuanlin Song +24 more
TL;DR: Although high fever was associated with the development of ARDS, it was also associated with better outcomes among patients with ARDS and treatment with methylprednisolone may be beneficial for patients who develop ARDS.
Journal ArticleDOI
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.
TL;DR: Results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China are described to identify possible means of non-respiratory transmission.
Journal ArticleDOI
Assessing the performance of prediction models: a framework for traditional and novel measures.
Ewout W. Steyerberg,Andrew J. Vickers,Nancy R. Cook,Thomas A. Gerds,Mithat Gonen,Nancy A Obuchowski,Michael J. Pencina,Michael W. Kattan +7 more
TL;DR: It is suggested that reporting discrimination and calibration will always be important for a prediction model and decision-analytic measures should be reported if the predictive model is to be used for clinical decisions.
Journal ArticleDOI
Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China.
Jin-jin Zhang,Xiang Dong,Yi yuan Cao,Ya-dong Yuan,Yi-bin Yang,You-qin Yan,Cezmi A. Akdis,Ya-dong Gao +7 more
TL;DR: This work aims to investigate the clinical characteristic and allergy status of patients infected with SARS‐CoV‐2 and its spread around the world.
Journal ArticleDOI
Evaluating the yield of medical tests
TL;DR: The treadmill exercise test is shown to provide surprisingly little prognostic information beyond that obtained from basic clinical measurements.
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