Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
Citations
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Short-Term Outcomes for Restorative and Non-Restorative Proctocolectomy in Older Adults
TL;DR: In this paper , the authors compared 30-day outcomes for restorative and non-restorative surgery in older adults with ulcerative colitis and found that patients undergoing restorative surgery were significantly younger (P<0.01), had lower incidences of steroid usage and higher rates of readmission (P = 0.02).
Journal ArticleDOI
Colectomy rates for ulcerative colitis over time: Navigating the evidence in the era of precision medicine and individualised treatment
TL;DR: Dai et al. as mentioned in this paper conducted a systematic review and meta-analysis of the literature to assess the rates of colectomy for ulcerative colitis over time, also comparing the pre-biologic vs biologic drug eras.
Posted ContentDOI
The long-term effect on surgery-free survival of biological compared to conventional therapy in Crohn’s disease in real world-data: a propensity-score matched study
TL;DR: In this paper , the authors evaluated the impact of biological versus conventional therapy on surgery-free survival time (from the diagnosis to the first bowel resection) and on the overall risk of surgery in patients with Crohn's disease (CD) who were never with the surgical option.
Journal ArticleDOI
Postoperative Crohn's Disease.
TL;DR: In this paper , a randomized controlled study suggested that infliximab is more likely to prevent endoscopic recurrence than placebo, but other biologicals have been used as well.
References
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI
Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more