Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
Citations
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Editorial: do thiopurines and biologics decrease the risk of colectomy?
Kristine H. Allin,T. Jess +1 more
TL;DR: It is hoped that these findings may guide clinicians moving forward in managing long-term treated asymptomatic coeliac disease patients with undetectable serology and no evidence of nutritional deficiencies.
Journal Article
The Impact of Biologic Therapy on Outcomes of Inflammatory Bowel Disease Surgery.
Journal ArticleDOI
Novel polyurethane based particulate formulations of infliximab reduce inflammation in DSS induced murine model of colitis - A preliminary study.
Ritesh M. Pabari,Murtaza M. Tambuwala,Natalia K. Lajczak-McGinley,Alaa A. A. Aljabali,Brian P. Kirby,Stephen J. Keely,Zebunissa Ramtoola +6 more
TL;DR: In this article, a dextran sodium sulfate (DSS) induced model of colitis was used to evaluate the severity of the colitis by measurement of disease activity index (DAI) score, inflammatory markers (neutrophil infiltration, TNFα) and histological score.
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Korean clinical practice guidelines on biologics for moderate to severe Crohn’s disease
Seong Joon Koh,Sung Noh Hong,Soo-Kyung Park,Byong Duk Ye,Kyeong Ok Kim,Jeong Eun Shin,Yong Sik Yoon,Hong Sub Lee,Sung-Hoon Jung,Mi-Rai Choi,Soo Young Na,Chang Hwan Choi,Joo Sung Kim +12 more
TL;DR: The third Korean guidelines for CD management provide updated information regarding treatment of moderate-to-severe CD patients with biologic agents, showing the non-inferiority of CT-P13, an infliximab biosimilar, compared with inflIXimab in CD patients.
Journal ArticleDOI
The risk of later surgery at the anastomotic site following right hemicolectomy for Crohn's disease in a national cohort of 12 230 patients.
Dominic King,Benjamin Coupland,Amandeep Dosanjh,Andrew Cole,Nicola J Adderley,Raoul C. Reulen,Prashant Patel,Nigel Trudgill +7 more
TL;DR: Crohn's disease has a high‐risk of bowel resection and later surgery for recurrent disease and recent guidelines recommend colonoscopy 6‐12 months following surgery to reduce further surgical intervention through medical therapy intensification.
References
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
Related Papers (5)
Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more